Chloroquine-astemizole hybrids with potent in vitro and in vivo antiplasmodial activity (Publications)
nt strain of Plasmodium falciparum, and examples 7 and 8 were active in vivo in mouse models of malaria
<em>Plasmodium falciparum</em> and <em>Plasmodium vivax</em> genotypes and efficacy of intermittent preventive treatment in Papua New Guinea (Publications)
Intermittent preventive treatment of infants (IPTi) reduces early-childhood malaria-related morbidity. While genotypic drug resistance markers have proven useful in predicting the efficacy of antimalarial
Blood transfusion for severe anaemia in children in a Kenyan hospital [Research letter] (Publications)
Severe anaemia often secondary to malaria is a major contributor to child mortality in sub-Saharan Africa. We have confirmed that use of simple clinical and laboratory criteria can identify those children
Ancistroheynine B and two further 7,3'-coupled naphthylisoquinoline alkaloids from<em> Ancistrocladus heyneanus</em> Wall (Publications)
c, and chiroptical methods. Biological activities of ancistroheynine B against the pathogens of malaria, leishmaniasis, Chagas' disease, and African sleeping sickness were evaluated
Ancistroheynine B and two further 7,3'-coupled naphthylisoquinoline alkaloids from<em> Ancistrocladus heyneanus</em> Wall (Publications)
c, and chiroptical methods. Biological activities of ancistroheynine B against the pathogens of malaria, leishmaniasis, Chagas' disease, and African sleeping sickness were evaluated
Blood transfusion for severe anaemia in children in a Kenyan hospital [Research letter] (Publications)
Severe anaemia often secondary to malaria is a major contributor to child mortality in sub-Saharan Africa. We have confirmed that use of simple clinical and laboratory criteria can identify those children
<em>Plasmodium falciparum</em> and <em>Plasmodium vivax</em> genotypes and efficacy of intermittent preventive treatment in Papua New Guinea (Publications)
Intermittent preventive treatment of infants (IPTi) reduces early-childhood malaria-related morbidity. While genotypic drug resistance markers have proven useful in predicting the efficacy of antimalarial
Chloroquine-astemizole hybrids with potent in vitro and in vivo antiplasmodial activity (Publications)
nt strain of Plasmodium falciparum, and examples 7 and 8 were active in vivo in mouse models of malaria
New 4-amino-2-azabicyclo[3.2.2]nonane derivatives and their antiprotozoal potencies (Publications)
East African sleeping sickness, Trypanosoma b. rhodesiense, and a protozoan parasite which causes Malaria tropica, Plasmodium falciparum K-1, a strain which is resistant to chloroquine and pyrimethamine
Incorporation of an intramolecular hydrogen bonding motif in the side chain of antimalarial benzimidazoles (Publications)
activity against chloroquine-sensitive (NF54) and multi-drug resistant (K1) strains of the human malaria parasite Plasmodium falciparum. Compounds were also screened for their cytotoxicity towards a mammalian