Design of trials for interrupting the transmission of endemic pathogens (Publications)
of the SolarMal trial on the use of odor-baited mosquito traps to eliminate Plasmodium falciparum malaria. These were used to compare variants in the proposed SWCRT designs for the SolarMal trial. RESULTS: [...] assessed in the simulated trials. Inspired by analyses of trials of insecticide-treated nets against malaria when applied to the geography of the SolarMal trial, these measures were found to be robust to different
<em>Plasmodium falciparum </em>infection and clinical indicators in relation to net coverage in central Côte d'Ivoire (Publications)
Sleeping under a net, particularly a long-lasting insecticidal net (LLIN), is associated with reduced malaria morbidity and mortality, but requires high coverage and adherence. In this study, parasitologically [...] and associations with net coverage explored. In Bozi and Yoho, LLINs were provided by the national malaria control programme, prior to the study and an additional catch-up coverage was carried out in Bozi
Mass distribution of free insecticide-treated nets do not interfere with continuous net distribution in Tanzania (Publications)
BACKGROUND: To protect the most vulnerable groups from malaria (pregnant women and infants) the Tanzanian Government introduced a subsidy (voucher) scheme in 2004, on the basis of a public-private partnership [...] for the continuation of this effort in Tanzania and for emulation by other countries with endemic malaria
Ownership and usage of mosquito nets after four years of large-scale free distribution in Papua New Guinea (Publications)
Guinea (PNG) is a highly malaria endemic country in the South-West Pacific with a population of approximately 6.6 million (2009). In 2004, the country intensified its malaria control activities with support
An evidence synthesis approach for combining different data sources illustrated using entomological efficacy of insecticides for indoor residual... (Publications)
BACKGROUND: Prospective malaria public health interventions are initially tested for entomological impact using standardised experimental hut trials. In some cases, data are collated as aggregated counts [...] residual spray (IRS) product active ingredient, used on wall surfaces to kill mosquitoes and reduce malaria transmission, were analysed using a series of statistical models to understand the benefits and
Prévention des infections chez les voyageurs immunosupprimés (Publications)
While traveling, patients may be exposed to several infections, such as traveler's diarrhea or malaria, which can be associated with a high rate of complications in this population. An appropriate strategy
Prévention des infections chez les voyageurs immunosupprimés (Publications)
While traveling, patients may be exposed to several infections, such as traveler's diarrhea or malaria, which can be associated with a high rate of complications in this population. An appropriate strategy
Sophie Diarra (People)
https://www.swisstph.ch/fr/staff/profile/people/sophie-diarra
of the Health Interventions Unit at Swiss TPH, Sophie is currently investigating key factors in malaria control, applying a socio-epidemiological approach in Papua New Guinea . Her key interests lie in
Osama Seidahmed (People)
https://www.swisstph.ch/fr/staff/profile/people/osama-seidahmed
c region. His work includes diverse operational outcomes in the battle against diseases such as malaria, dengue, Chikungunya, and Rift Valley fever. He also contributed to the teaching at a college level
Modified 5'-trityl nucleosides as inhibitors of <em>Plasmodium falciparum</em> dUTPase (Publications)
dine triphosphate nucleotidohydrolase (dUTPase) is a potential drug target for the treatment of malaria. We previously reported the discovery of 5'-tritylated analogues of deoxyuridine as selective inhibitors