Sustaining LLIN coverage with continuous distribution: the school net programme in Tanzania (Publications)
Most malaria-endemic countries have struggled in the past decade to establish effective national-scale continuous distribution mechanisms for long-lasting insecticidal nets (LLINs). Since the implementation
The cost-effectiveness of permethrin impregnated bednets in preventing child mortality in Kassena-Nankana district of Northern Ghana (Publications)
bednets are now being widely promoted as an effective means of protecting African children against malaria, but there is little evidence of their cost-effectiveness. The impact on child mortality of introducing
Drug repurposing in the chemotherapy of infectious diseases (Publications)
attack that are divergent share common ancestry (e.g., prokaryotic targets in the apicoplast of malaria parasites), whereas those that are convergent arise from a shared lifestyle (e.g., the susceptibility
Genetic validation of <em>Pf</em>FKBP35 as an antimalarial drug target (Publications)
Plasmodium falciparum accounts for the majority of over 600,000 malaria-associated deaths annually. Parasites resistant to nearly all antimalarials have emerged and the need for drugs with alternative
Different classes of genomic inserts contribute to human antibody diversity (Publications)
elements from distant genes in antibody transcripts. Independent of the preexposure of donors to malaria parasites, non-VDJ inserts were detected in 80% of individuals at frequencies of 1 in 10(4) to 10(5)
Small-scale field evaluation of PermaNet® Dual (a long-lasting net coated with a mixture of chlorfenapyr and deltamethrin) against... (Publications)
BACKGROUND: Due to the rapid expansion of pyrethroid-resistance in malaria vectors in Africa, Global Plan for Insecticide Resistance Management (GPIRM) has recommended the development of long-lasting [...] populations. PermaNet((R)) Dual thus represents a promising tool, with a high potential to reduce malaria transmission and provide community protection in areas compromised by mosquito vector resistance
Strategies for understanding and reducing the <em>Plasmodium vivax</em> and <em>Plasmodium ovale</em> hypnozoite reservoir in Papua New Guinean... (Publications)
undetectable hypnozoite reservoir for relapsing Plasmodium vivax and P. ovale malarias presents a major challenge for malaria control and elimination in endemic countries. This study aims to directly determine
Strategies for understanding and reducing the <em>Plasmodium vivax</em> and <em>Plasmodium ovale</em> hypnozoite reservoir in Papua New Guinean... (Publications)
undetectable hypnozoite reservoir for relapsing Plasmodium vivax and P. ovale malarias presents a major challenge for malaria control and elimination in endemic countries. This study aims to directly determine
Small-scale field evaluation of PermaNet® Dual (a long-lasting net coated with a mixture of chlorfenapyr and deltamethrin) against... (Publications)
BACKGROUND: Due to the rapid expansion of pyrethroid-resistance in malaria vectors in Africa, Global Plan for Insecticide Resistance Management (GPIRM) has recommended the development of long-lasting [...] populations. PermaNet((R)) Dual thus represents a promising tool, with a high potential to reduce malaria transmission and provide community protection in areas compromised by mosquito vector resistance
Global metabolic responses of NMRI mice to an experimental <em>Plasmodium berghei</em> infection (Publications)
metabolic profiling may provide a sensitive diagnostic tool of Plasmodium infection and the control of malaria more generally