Transcontinental spread and evolution of <em>Mycobacterium tuberculosis </em>W148 European/Russian clade toward extensively drug resistant... (Publications)
Transmission-driven multi-/extensively drug resistant (M/XDR) tuberculosis (TB) is the largest single contributor to human mortality due to antimicrobial resistance. A few major clades of the Mycobact
<em>In vitro</em> antiplasmodial activity and cytotoxicity of extracts and chromatographic fractions of twigs from <em>Pappea capensi</em>s EckI &... (Publications)
ETHNOPHARMACOLOGICAL RELEVANCE: The Vha-Venda people of South Africa use Pappea capensis EckI & Zeyh. (Sapindaceae) twigs to treat malaria and its related symptoms. AIM OF STUDY: The main aim of this
Care seeking and treatment of febrile children with and without danger signs of severe disease in northern Uganda: results from three household... (Publications)
Identification, stabilization, and prompt referral of children with signs of severe febrile disease (danger signs) in rural communities are crucial for preventing complications and death from severe m
Putative biomarkers of environmental enteric disease fail to correlate in a cross-sectional study in two study sites in Sub-Saharan Africa (Publications)
Environmental enteric dysfunction (EED) is an elusive, inflammatory syndrome of the small intestine thought to be associated with enterocyte loss and gut leakiness and lead to stunted child growth. To
The communication chain of genetic risk: analyses of narrative data exploring proband-provider and proband-family communication in hereditary breast... (Publications)
Low uptake of genetic services among members of families with hereditary breast and ovarian cancer (HBOC) suggests limitations of proband-mediated communication of genetic risk. This study explored ho
A tiered approach for assessing individual and combined risk of pyrethroids using human biomonitoring data (Publications)
Pyrethroids are a major insecticide class, suitable for biomonitoring in humans. Due to similarities in structure and metabolic pathways, urinary metabolites are common to various active substances. A
Efficacy and safety of moxidectin and albendazole compared with ivermectin and albendazole coadministration in adolescents infected with <em>Trichuris... (Publications)
BACKGROUND: Control efforts against soil-transmitted helminths focus on preventive chemotherapy with albendazole and mebendazole, however these drugs yield unsatisfactory results against Trichuris tri
Genetically modified malaria parasites as vaccine candidates (Publications)
Induction of sterile immunity against sporozoite and liver stages of malaria is a long-standing aim in vaccine development. Genetically engineered, attenuated sporozoites were systematically evaluated