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1. Aryl hydantoin Ro 13-3978, a broad-spectrum antischistosomal (Publications)

   Aryl hydantoin Ro 13-3978, a broad-spectrum antischistosomal

   Pertinence:

   OBJECTIVES: Praziquantel is the only drug available for the treatment of schistosomiasis and the state of the exhausted drug discovery pipeline is alarming. We restarted investigations on the abandone

2. Design of a phase III cluster randomized trial to assess the efficacy and safety of a malaria transmission blocking vaccine (Publications)

   Design of a phase III cluster randomized trial to assess the efficacy and safety of a malaria transmission blocking vaccine

   Pertinence:

   Vaccines interrupting Plasmodium falciparum malaria transmission targeting sexual, sporogonic, or mosquito-stage antigens (SSM-VIMT) are currently under development to reduce malaria transmission. An

3. Perspectives of family members participating in cultural assessment of psychiatric disorders: findings from the DSM-5 international field trial (Publications)

   Perspectives of family members participating in cultural assessment of psychiatric disorders: findings from the DSM-5 international field trial

   Pertinence:

   Abstract Despite the important roles families play in the lives of many individuals with mental illness across cultures, there is a dearth of data worldwide on how family members perceive the process

4. Efficacy and safety of albendazole plus ivermectin, albendazole plus mebendazole, albendazole plus oxantel pamoate, and mebendazole alone against... (Publications)

   Efficacy and safety of albendazole plus ivermectin, albendazole plus mebendazole, albendazole plus oxantel pamoate, and mebendazole alone against <em>Trichuris trichiura</em> and concomitant soil-transmitted helminth infections: a four-arm, randomised con

   Pertinence:

   BACKGROUND: Existing anthelmintic drugs (eg, albendazole and mebendazole) have low efficacy against the intestinal nematode species Trichuris trichiura and the drug pipeline is exhausted. We aimed to

5. Can a compact pre-filled auto-disable injection system (cPAD) save costs for DTP-HepB-Hib vaccine as compared with single-dose (SDV) and multi-dose... (Publications)

   Can a compact pre-filled auto-disable injection system (cPAD) save costs for DTP-HepB-Hib vaccine as compared with single-dose (SDV) and multi-dose vials (MDV)? Evidence from Cambodia, Ghana, and Peru

   Pertinence:

6. Power analysis for generalized linear mixed models in ecology and evolution (Publications)

   Power analysis for generalized linear mixed models in ecology and evolution

   Pertinence:

7. Apathy in Parkinson's disease is related to executive function, gender and age but not to depression (Publications)

   Apathy in Parkinson's disease is related to executive function, gender and age but not to depression

   Pertinence:

   Deficits in executive functions occur in up to 93% of patients with Parkinson's disease (PD). Apathy, a reduction of motivation and goal-directed behavior is an important part of the syndrome; affecti

8. Spatial and temporal distribution of soil-transmitted helminth infection in sub-Saharan Africa: a systematic review and geostatistical meta-analysis (Publications)

   Spatial and temporal distribution of soil-transmitted helminth infection in sub-Saharan Africa: a systematic review and geostatistical meta-analysis

   Pertinence:

   BACKGROUND: Interest is growing in predictive risk mapping for neglected tropical diseases (NTDs), particularly to scale up preventive chemotherapy, surveillance, and elimination efforts. Soil-transmi

9. Elucidation of the<em> in vitro</em> and <em>in vivo</em> activities of bridged 1,2,4-trioxolanes, bridged 1,2,4,5-tetraoxanes, tricyclic... (Publications)

   Elucidation of the<em> in vitro</em> and <em>in vivo</em> activities of bridged 1,2,4-trioxolanes, bridged 1,2,4,5-tetraoxanes, tricyclic monoperoxides, silyl peroxides, and hydroxylamine derivatives against <em>Schistosoma mansoni.</em>

   Pertinence:

   Praziquantel is currently the only drug available to treat schistosomiasis. Since drug resistance would be a major barrier for the increasing global attempts to eliminate schistosomiasis as a public h

10. Obesity paradox among type 2 diabetes: link between obesity and chronic kidney disease (Publications)

    Obesity paradox among type 2 diabetes: link between obesity and chronic kidney disease

    Pertinence: