Molecular basis for covalent inhibition of glyceraldehyde-3-phosphate dehydrogenase by a 2-phenoxy-1,4-naphthoquinone small molecule (Publications)
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) has recently gained attention as an anti-protozoan and anti-cancer drug target. We have previously identified 2-phenoxy-1,4-naphthoquinone as an inhibi
Seasonal pattern of <em>Mycobacterium ulcerans</em>, the causative agent of Buruli ulcer, in the environment in Ghana (Publications)
This study aimed to contribute to the understanding of Mycobacterium ulcerans (MU) ecology by analysing both clinical and environmental samples collected from ten communities along two major river bas
Quality of life as predictor for the development of cardiac ischemia in high-risk asymptomatic diabetic patients (Publications)
BACKGROUND: Ischemia induced by psychological stress and depression is a common phenomenon in stable coronary artery disease (CAD). We evaluated the quality of life (QoL) of diabetic patients screened
Attitudes of orthopedic specialists toward effects of medical device purchasing (Publications)
OBJECTIVES: The aim of this study was to assess viewpoints of end-users concerning the purchasing process of high-risk medical devices and to discuss the relevance of health technology assessments (HT
Phenotypes of atopic dermatitis depending on the timing of onset and progression in childhood (Publications)
Importance: Atopic dermatitis is an inflammatory, pruritic skin disease that often occurs in early infancy with a chronic course. However, a specific description of subtypes of atopic dermatitis depen
Epidemiological analysis of ozone and nitrogen impacts on vegetation - critical evaluation and recommendations (Publications)
For human health studies, epidemiology has been established as important tool to examine factors that affect the frequency and distribution of disease, injury, and other health-related events in a def