A single LC-tandem mass spectrometry method for the simultaneous determination of 14 antimalarial drugs and their metabolites in human plasma (Publications)
Among the various determinants of treatment response, the achievement of sufficient blood levels is essential for curing malaria. For helping us at improving our current understanding of antimalarial
Lack of multiple copies of pfmdr1 gene in Papua New Guinea (Publications)
We describe here the results of an analysis of Plasmodium falciparum multidrug resistance protein 1 (pfmdr1) gene copy number from 440 field isolates from Papua New Guinea. No multiple copies of the g
Risk factors for meningococcal meningitis in nothern Ghana (Publications)
Meningococcal meningitis is a major cause of morbidity and mortality in the meningitis belt of sub-Saharan Africa where it occurs in epidemics every 8-12 years. Risk factors for the disease in this se
Prioritization of prevention activities to combat the spread of HIV/AIDS in resource constrained settings: a cost-effectiveness analysis from Chad,... (Publications)
In Chad, as in most sub-Saharan Africa countries, HIV/AIDS poses a massive public health threat as well as an economic burden, with prevalence rates estimated at 9% of the adult population. In definin
<em>In vitro</em> and <em>in vivo</em> activity of 3-alkoxy-1,2-dioxolanes against <em>Schistosoma mansoni</em> (Publications)
OBJECTIVES: Compounds characterized by a peroxidic skeleton are an interesting starting point for antischistosomal drug discovery. Previously a series of 3-alkoxy-1,2-dioxolanes, which are chemically
Parental occupational exposure to extremely low frequency magnetic fields and childhood cancer: a German case-control study (Publications)
Extremely low frequency magnetic fields (ELF-MFs) have been classified as possibly carcinogenic to humans by the International Agency for Research on Cancer. The authors investigated, in a population-
Searching for new cures for tuberculosis: design, synthesis, and biological evaluation of 2-methylbenzothiazoles (Publications)
The actual development and clinical use of new therapeutics for tuberculosis (TB) have remained stagnant for years because of the complexity of the disease process, the treatment of which at present r