Alkaloids from <em>Nerine filifolia</em> (Publications)
The novel compounds N-demethylbelladine, 6alpha-methoxybuphanidrine and filifoline, in addition to five known alkaloids, and phenol have been isolated from fresh bulbs of Nerine filifolia (Amaryllidac
Case definitions of clinical malaria under different transmission conditions in Kilifi District, Kenya (Publications)
Background. Clear case definitions of malaria are an essential means of evaluating the effectiveness of present and proposed interventions in malaria. The clinical signs of malaria are nonspecific, an
MAP kinase kinase 1 (MKK1) is essential for transmission of <em>Trypanosoma brucei</em> by <em>Glossina morsitans</em> (Publications)
MAP kinase kinase 1 (MKK1) is encoded by a single copy gene in Trypanosoma brucei. It has been shown recently that MKK1 is not essential for bloodstream forms [14]. To investigate the requirement for
Use of B-type natriuretic peptide in the management of acute dyspnea in patients with pulmonary disease (Publications)
BACKGROUND: In patients with pulmonary disease, it is often challenging to distinguish exacerbated pulmonary disease from congestive heart failure (CHF). The impact of B-type natriuretic peptide (BNP)
Critical roles of glycosylphosphatidylinositol for <em>Trypanosoma brucei</em> (Publications)
Trypanosoma brucei, the protozoan parasite responsible for sleeping sickness, evades the immune response of mammalian hosts and digestion in the gut of the insect vector by means of its coat proteins
A Trk/HKT-type K+ transporter from <em>Trypanosoma brucei</em> (Publications)
The molecular mechanisms of K(+) homeostasis are only poorly understood for protozoan parasites. Trypanosoma brucei subsp. parasites, the causative agents of human sleeping sickness and nagana, are st
