The influence of jittering DHS cluster locations on geostatistical model-based estimates of malaria risk in Cameroon (Publications)
Background In low-and-middle income countries, national representative household surveys such as the Demographic and Health Surveys (DHS) and the Malaria Indicator Surveys (MIS) are routinely carried
Effect of a youth-led early childhood care and education programme on children's development and learning in rural Sindh, Pakistan (LEAPS): a... (Publications)
BACKGROUND: In low-income and middle-income countries, an estimated 181·9 million (74·6%) preschool-aged children do not receive adequate nurturing care in health, nutrition, protection, learning, and
Body weight changes in people with HIV starting dolutegravir versus efavirenz-based regimens in a large cohort in rural Tanzania (Publications)
OBJECTIVES: To analyze weight changes associated with dolutegravir- versus efavirenz-based antiretroviral therapy (ART) in people living with HIV (PLHIV) in rural Tanzania, where undernutrition is pre
A potent and selective reaction hijacking inhibitor of <em>Plasmodium falciparum</em> tyrosine tRNA synthetase exhibits single dose oral efficacy... (Publications)
The Plasmodium falciparum cytoplasmic tyrosine tRNA synthetase (PfTyrRS) is an attractive drug target that is susceptible to reaction-hijacking by AMP-mimicking nucleoside sulfamates. We previously id
Perceptions of roles of community healthcare workers in early childhood in Limpopo, South Africa (Publications)
BACKGROUND: As part of the Reengineering Primary Health Care initiative, the South African National Department of Health (NDoH) has committed to expanding access to home-based care provided by communi
Participation in organised sports and longitudinal development of physical activity in Swiss youth: the population-based SOPHYA cohort (Publications)
BACKGROUND: Maintaining physical activity throughout life is crucial for overall health and wellbeing. Yet the age-related decline in average physical activity, a natural phenomenon also observed in a
Pharmacometric analysis to describe pharmacokinetics and exposure-efficacy response of ivermectin in adolescents infected with <em>Trichuris... (Publications)
The efficacy of the combination therapy of albendazole and ivermectin against Trichuris trichiura infection is higher in Tanzania than in Côte d'Ivoire. This study therefore aimed to investigate the d
Feasibility and acceptability of the Problem Management for Moms programme for improving maternal mental health in Zambia: an open-label trial (Publications)
BACKGROUND: Psychological distress is common among mothers in low-income and middle-income countries, limiting their capacity to care for themselves and their children. This study aimed to test the fe