Assessment of global reporting of adverse drug reactions for anti-malarials, including artemisinin-based combination therapy, to the WHO Programme for... (Publications)
BACKGROUND: In spite of enhanced control efforts, malaria remains a major public health problem causing close to a million deaths annually. With support from several donors, large amounts of artemisin
Clinical presentation of <em>T.b. rhodesiense</em> sleeping sickness in second stage patients from Tanzania and Uganda (Publications)
BACKGROUND: A wide spectrum of disease severity has been described for Human African Trypanosomiasis (HAT) due to Trypanosoma brucei rhodesiense (T.b. rhodesiense), ranging from chronic disease patter
Increased use of malaria rapid diagnostic tests improves targeting of anti-malarial treatment in rural Tanzania: implications for nationwide rollout... (Publications)
BACKGROUND: The World Health Organization recommends parasitological confirmation of all malaria cases. Tanzania is implementing a phased rollout of malaria rapid diagnostic tests (RDTs) for routine u
Anti-protozoal activity of aporphine and protoberberine alkaloids from <em>Annickia kummeriae</em> (Engl. & Diels) Setten & Maas (Annonaceae) (Publications)
BACKGROUND: Malaria, trypanosomiasis and leishmaniasis have an overwhelming impact in the poorest countries in the world due to their prevalence, virulence and drug resistance ability. Currently, ther
The usefulness of twenty-four molecular markers in predicting treatment outcome with combination therapy of amodiaquine plus... (Publications)
BACKGROUND: In Papua New Guinea (PNG), combination therapy with amodiaquine (AQ) or chloroquine (CQ) plus sulphadoxine-pyrimethamine (SP) was introduced as first-line treatment against uncomplicated m
A pilot control trial of schistosomiasis in central Liberia by mass chemotherapy of target populations, combined with focal application of... (Publications)
In an area of high transmission of Schistosoma haematobium and S. mansoni in Central Liberia, populations of five villages and intermediate host snails were surveyed for two years. In three of these v
