Travel-related health risks in moderately and severely immunocompromised patients: a case-control study (Publications)
BACKGROUND: The number of immunocompromised persons travelling to tropical countries is increasing. The hypothesis is that this population is at increased risk of travel-related health problems but th
Travellers' profile, travel patterns and vaccine practices - a 10-year prospective study in a Swiss Travel Clinic (Publications)
BACKGROUND: The travel clinic in Lausanne serves a catchment area of 700 000 of inhabitants and provides pre- and post-travel consultations. This study describes the profile of attendees before depart
Local cellular immune responses and pathogenesis of Buruli ulcer lesions in the experimental <em>Mycobacterium ulcerans</em> pig infection model (Publications)
BACKGROUND: Buruli ulcer is a neglected tropical disease of the skin that is caused by infection with Mycobacterium ulcerans. We recently established an experimental pig (Sus scrofa) infection model f
Local heat application for the treatment of Buruli ulcer: results of a phase II open label single center non comparative clinical trial (Publications)
BACKGROUND: Buruli ulcer (BU) is a necrotising skin disease most prevalent among West African children. The causative organism, Mycobacterium ulcerans, is sensitive to temperatures above 37 degrees C.
Effectiveness of a home-based counselling strategy on neonatal care and survival: a cluster-randomised trial in six districts of rural southern... (Publications)
BACKGROUND: We report a cluster-randomised trial of a home-based counselling strategy, designed for large-scale implementation, in a population of 1.2 million people in rural southern Tanzania. We hyp
Spatial distribution of <em>Mycobacterium ulcerans</em> in Buruli ulcer lesions: implications for laboratory diagnosis (Publications)
BACKGROUND: Current laboratory diagnosis of Buruli ulcer (BU) is based on microscopic detection of acid fast bacilli, quantitative real-time PCR (qPCR), histopathology or cultivation. Insertion sequen
Comparative study of activities of a diverse set of anti-mycobacterial agents against <em>Mycobacterium tuberculosis</em> and <em>Mycobacterium... (Publications)
A library of compounds covering a broad chemical space was selected from a tuberculosis drug development program and screened in a whole cell assay against Mycobacterium ulcerans, the causative agent
