Recherche de *.

1. Development and adaptation of tensile strength by bones in the extremities in response to physical training exemplified by the tibia (Publications)

   Development and adaptation of tensile strength by bones in the extremities in response to physical training exemplified by the tibia

   Pertinence:

   Results from an in vivo assessment of the bending stiffness of human tibiae with a new method demonstrate that bone mineral measurements are not a suitable predictor to evaluate changes of mechanical

2. Betraying the parasite's redox system: diaryl sulfide-based inhibitors of trypanothione reductase: subversive substrates and antitrypanosomal... (Publications)

   Betraying the parasite's redox system: diaryl sulfide-based inhibitors of trypanothione reductase: subversive substrates and antitrypanosomal properties

   Pertinence:

3. Diaryl sulfide-based inhibitors of trypanothione reductase: inhibition potency, revised binding mode and antiprotozoal activities (Publications)

   Diaryl sulfide-based inhibitors of trypanothione reductase: inhibition potency, revised binding mode and antiprotozoal activities

   Pertinence:

   Trypanothione reductase (TR) is an essential enzyme of trypanosomatids and therefore a promising target for the development of new drugs against African sleeping sickness and Chagas' disease. Diaryl s

4. Methods development for epidemiologic investigations of the health effects of prolonged ozone exposure. Part I: Variability of pulmonary function... (Publications)

   Methods development for epidemiologic investigations of the health effects of prolonged ozone exposure. Part I: Variability of pulmonary function measures

   Pertinence:

   The acute and subacute effects of ambient concentrations of ozone on lung function have been studied extensively in a variety of settings. Such studies generally have focused on measures of function t

5. Methods development for epidemiologic investigations of the health effects of prolonged ozone exposure. Part II. An approach to retrospective... (Publications)

   Methods development for epidemiologic investigations of the health effects of prolonged ozone exposure. Part II. An approach to retrospective estimation of lifetime ozone exposure using a questionnaire and ambient monitoring data (California sites)

   Pertinence:

   An extensive body of data supports a relation between acute exposures to ambient ozone and the occurrence of various acute respiratory symptoms and changes in measures of lung function. In contrast, r

6. Synthesis and antimalarial property of orally active phenoxazinium salts (Publications)

   Synthesis and antimalarial property of orally active phenoxazinium salts

   Pertinence:

   Phenoxazinium salts were found to display good antimalarial efficacy in vivo against Plasmodium berghei. Several compounds provided 100% parasitemia clearance at a dose of 20-30 mg kg-1x4 days (ip) an

7. The science of elimination in practice (Publications)

   The science of elimination in practice

   Pertinence:

8. Synthesis, antiprotozoal and cytotoxic activities of new N-(3,4-dimethyl-5-isoxazolyl)-1,2-naphthoquinone-4-amino derivatives (Publications)

   Synthesis, antiprotozoal and cytotoxic activities of new N-(3,4-dimethyl-5-isoxazolyl)-1,2-naphthoquinone-4-amino derivatives

   Pertinence:

   Three derivatives of N-(3,4-dimethyl-5-isoxazolyl)-1,2-naphthoquinone-4-amino (1), a compound which exhibits significant activity against Trypanosoma cruzi and Plasmodium falciparum but with cytotoxic

9. Antimalarial activity of novel pyrrolizidinyl derivatives of 4-aminoquinoline (Publications)

   Antimalarial activity of novel pyrrolizidinyl derivatives of 4-aminoquinoline

   Pertinence:

   Two pyrrolizidinylalkyl derivatives of 4-amino-7-chloroquinoline (MG2 and MG3) were prepared and tested in vitro against CQ-sensitive and CQ-resistant strains of Plasmodium falciparum and in vivo in a

10. International research workshop on health-related stigma and discrimination (Publications)

    International research workshop on health-related stigma and discrimination

    Pertinence: