Medicinal chemistry optimization of antiplasmodial imidazopyridazine hits from high throughput screening of a softfocus kinase library: part 2 (Publications)
On the basis of our recent results on a novel series of imidazopyridazine-based antimalarials, we focused on identifying compounds with improved aqueous solubility and hERG profile while maintaining m
Stimulation of hamster and human lymphocyte cultures by soluble egg antigens (SEA) of <em>Schistosoma haematobium </em>and <em>S. mansoni</em> (Publications)
Soluble egg and adult worm antigen preparations of Schistosoma haematobium and S. mansoni were tested in hamster and human lymphocyte cultures. Primed lymphocytes from infected donors showed a marked