Efficacy and safety of moxidectin and albendazole compared to ivermectin and albendazole co-administration in adolescents infected with <em>Trichuris... (Publications)
Background: Infections with soil-transmitted helminths (STHs) predominantly affect impoverished populations in tropical environments. The periodic administration of single dose benzimidazoles (i.e., a
Long-term health sequelae and quality of life at least 6 months after infection with SARS-CoV-2: design and rationale of the COVIDOM-study as part of... (Publications)
PURPOSE: Over the course of COVID-19 pandemic, evidence has accumulated that SARS-CoV-2 infections may affect multiple organs and have serious clinical sequelae, but on-site clinical examinations with
Investigation of <em>Mycobacterium ulcerans</em> glycan interactions using glycan array and surface plasmon resonance (Publications)
Many pathogenic bacteria utilize glycan-based interactions to bind to host cells. Glycan array analysis and surface plasmon resonance are glycobioanalytical techniques that have been used to investiga
Immunohistochemistry: a method to analyze<em> M. ulcerans </em>infected skin tissue (Publications)
Immunohistochemistry (IHC) is a combination of immunological, biochemical, and pathological methods to visualize the presence and distribution of specific epitopes in tissue sections. Selected antigen
Competitive ELISA for the detection and quantification of<em> Mycobacterium ulcerans </em>mycolactone (Publications)
Lipids and other hydrophobic analytes are difficult to quantify by routine immunoassays due to the need to use aqueous buffers. Here, we describe an ELISA protocol suitable for the detection of mycola
Overview: development of drugs against<em> Mycobacterium ulcerans</em> (Publications)
For many years, wide margin surgical excision of Buruli ulcer lesions has been the main approach for the treatment of Mycobacterium ulcerans disease. The WHO now recommends an eight-week course of ora
Longer delays in diagnosis and treatment of pulmonary tuberculosis in pastoralist setting, Eastern Ethiopia (Publications)
Purpose: This study aimed to assess the extent of patient, health system and total delays in diagnosis and treatment of pulmonary tuberculosis (TB) in Somali pastoralist setting, Ethiopia. Patients an
Household factors associated with access to insecticide-treated nets and house modification in Bagamoyo and Ulanga districts, Tanzania (Publications)
BACKGROUND: Insecticide-treated nets (ITNs) and house modifications are proven vector control tools, yet in most regions, full coverage has not been achieved. This study investigates household factors
Lignans, amides, and saponins from <em>Haplophyllum tuberculatum</em> and their antiprotozoal activity (Publications)
A screening of Sudanese medicinal plants for antiprotozoal activities revealed that the chloroform and water fractions of the ethanolic root extract of Haplophyllum tuberculatum exhibited appreciable
Patterns of cross-sectional and predictive physical activity in Swiss adults aged 52+: results from the SAPALDIA cohort (Publications)
BACKGROUND: Non-communicable diseases (NCDs) account for the vast majority of deaths in Switzerland. Insufficient physical activity (PA) is an established NCD risk factor and PA is known to be benefic
