SCYX-7158, an orally-active benzoxaborole for the treatment of stage 2 human African trypanosomiasis (Publications)
BACKGROUND: Human African trypanosomiasis (HAT) is an important public health problem in sub-Saharan Africa, affecting hundreds of thousands of individuals. An urgent need exists for the discovery and
Soil-transmitted helminth reinfection after drug treatment: a systematic review and meta-analysis (Publications)
BACKGROUND: Soil-transmitted helminth (STH) infections (i.e., Ascaris lumbricoides, hookworm, and Trichuris trichiura) affect more than a billion people. Preventive chemotherapy (i.e., repeated admini
Our exciting journey to ACT-451840 (Publications)
We describe our work resulting in the selection of ACT-451840 ( 38 ) as a novel antimalarial drug with a novel mode of action. The compound was broadly characterized in vitro as well as in vivo in rat
37 years of forest monitoring in Switzerland: drought effects on<em> Fagus sylvatica</em> (Publications)
European beech is one of the most important deciduous tree species in natural forest ecosystems in Central Europe. Its dominance is now being questioned by the emerging drought damages due to the incr
Changes in household wealth in communities living in proximity to a large-scale copper mine in Zambia (Publications)
Large-scale mining can alter the living conditions of surrounding communities in positive and negative ways. A health impact assessment conducted in the context of a newly developed large-scale copper
