More than one way to produce protein diversity: duplication and limited alternative splicing of an adhesion molecule gene in basal arthropods (Publications)
Exon duplication and alternative splicing evolved multiple times in metazoa and are of overall importance in shaping genomes and allowing organisms to produce many fold more proteins than there are ge
Cutaneous leishmaniasis in Switzerland: first experience with species-specific treatment (Publications)
BACKGROUND: Different species of the genus Leishmania can cause cutaneous (CL) and mucosal leishmaniasis (ML). PCR-based tests allow a rapid diagnosis and determination of the species, thereby enablin
Mathematical models of contact patterns between age groups for predicting the spread of infectious diseases (Publications)
The spread of an infectious disease is sensitive to the contact patterns in the population and to precautions people take to reduce the transmission of the disease. We investigate the impact that diff
Improved characterization of visual evoked potentials in multiple sclerosis by topographic analysis (Publications)
In multiple sclerosis (MS), the combination of visual, somatosensory and motor evoked potentials (EP) has been shown to be highly correlated with the Expanded Disability Severity Scale (EDSS) and to p
Reduced neurobehavioral impairment from sleep deprivation in older adults: contribution of adenosinergic mechanisms (Publications)
A night without sleep is followed by enhanced sleepiness, increased low-frequency activity in the waking EEG, and reduced vigilant attention. The magnitude of these changes is highly variable among he
Anti-protozoal activities of cembrane-type diterpenes from Vietnamese soft corals (Publications)
Based on our previous finding that certain cembranoid diterpenes possess selective toxicity against protozoan pathogens of tropical diseases such as Trypanosoma and Plasmodium, we have subjected a ser
Chimerization at the AQP2-AQP3 locus is the genetic basis of melarsoprol-pentamidine cross-resistance in clinical<em> Trypanosoma</em> <em>brucei... (Publications)
Aquaglyceroporin-2 is a known determinant of melarsoprol-pentamidine cross-resistance in Trypanosoma brucei brucei laboratory strains. Recently, chimerization at the AQP2-AQP3 tandem locus was describ
Children's personal exposure measurements to extremely low frequency magnetic fields in Italy (Publications)
Extremely low frequency magnetic fields (ELF-MFs) exposure is still a topic of concern due to their possible impact on children's health. Although epidemiological studies claimed an evidence of a poss
<em>In silico</em> identification and <em>in vitro</em> activity of novel natural inhibitors of <em>Trypanosoma brucei</em>... (Publications)
As part of our ongoing efforts to identify natural products with activity against pathogens causing neglected tropical diseases, we are currently performing an extensive screening of natural product (
