Synthesis, DNA affinity, and antiprotozoal activity of fused ring dicationic compounds and their prodrugs (Publications)
Dicationic guanidine, N-alkylguanidine, and reversed amidine derivatives of fused ring systems have been synthesized from their corresponding bis-amines. DNA binding studies suggest that the diguanidi
Successful booster antibody response up to 54 months after single primary vaccination with virosome-formulated, aluminum-free hepatitis A vaccine (Publications)
This study demonstrates that a booster dose of the virosome-formulated, aluminum-free hepatitis A vaccine Epaxal (Berna Biotech) is highly immunogenic in subjects who received a single primary dose of
Skin lesions, malaise, and heart failure in a renal transplant recipient (Publications)
A male Caucasian patient developed nodular erythematous skin lesions, malaise, and clinical signs of progressive heart failure 4 months after renal transplantation. Bronchoscopy with bronchoalveolar l
Rise in malaria incidence rates in South Africa: a small-area spatial analysis of variation in time trends (Publications)
Using Bayesian statistical models, the authors investigated spatial and temporal variations in small-area malaria incidence rates for the period mid-1986 to mid-1999 for two districts in northern KwaZ
Genetic association with response to intravitreal ranibizumab in patients with neovascular AMD (Publications)
Purpose. Neovascular age-related macular degeneration (AMD) resulting in decreased central vision severely impairs affected individuals. Current standard treatment is an intravitreal anti-VEGF therapy
Activity of OZ78 analogues against <em>Fasciola hepatica</em> and <em>Echinostoma caproni</em> (Publications)
The rapid spread of triclabendazole resistance in veterinary medicine is an important motivation for fasciocidal drug discovery and development. The aim of this study was to characterize the fasciocid