Characterisation of a melamino nitroheterocycle as a potential lead for the treatment of human African trypanosomiasis (Publications)
This paper reports an evaluation of a melamine-nitroheterocycle, a potential lead for further development as an agent against human African trypanosomiasis (HAT). Studies on its efficacy, physicochemi
A tradition and an epidemic: determinants of the campylobacteriosis winter peak in Switzerland (Publications)
Campylobacteriosis is the most frequently reported food borne infection in Switzerland. We investigated determinants of infections and illness experience in wintertime. A case-control study was conduc
The search for underlying principles of health impact assessment: progress and prospects: comment on "Investigating underlying principles to guide... (Publications)
Health Impact Assessment (HIA) is a relatively young field of endeavour, and hence, future progress will depend on the planning, implementation and rigorous evaluation of additional HIAs of projects,
<em>In vitro</em> and<em> In vivo</em> evaluation of 28DAP010, a novel diamidine for treatment of second-stage African sleeping sickness (Publications)
African sleeping sickness is a neglected tropical disease transmitted by tsetse flies. New and better drugs are still needed especially for its second stage, which is fatal if untreated. 28DAP010, a d
Pyridyl benzamides as a novel class of potent inhibitors for the kinetoplastid <em>Trypanosoma brucei</em> (Publications)
A whole-organism screen of approximately 87000 compounds against Trypanosoma brucei brucei identified a number of promising compounds for medicinal chemistry optimization. One of these classes of comp