Small scale migration along the interoceanic highway in Madre de Dios, Peru: an exploration of community perceptions and dynamics due to migration (Publications)
BACKGROUND: Madre de Dios, a southern state in the Peruvian Amazon basin, has experienced rapid development as well as an influx of migrants since the construction of the Interoceanic Highway (IOH) co
<em>In silico</em> guided reconstruction and analysis of ICAM-1-binding var genes from <em>Plasmodium falciparum</em> (Publications)
The Plasmodium falciparum variant surface antigen PfEMP1 expressed on the surface of infected erythrocytes is thought to play a major role in the pathology of severe malaria. As the sequence pool of t
High-throughput metabolomic analysis predicts mode of action of uncharacterized antimicrobial compounds (Publications)
Rapidly spreading antibiotic resistance and the low discovery rate of new antimicrobial compounds demand more effective strategies for early drug discovery. One bottleneck in the drug discovery pipeli
Georatusin, a specific antiparasitic polyketide-peptide hybrid from the gungus <em>Geomyces auratus</em> (Publications)
Georatusin (1), featuring a highly reduced, methylated polyketide moiety fused to a tryptophan by an amide and ester bond forming a 13-membered ring, was produced by the soil fungus Geomyces auratus.
Effect of an integrated intervention package of preventive chemotherapy, community-led total sanitation and health education on the prevalence of... (Publications)
BACKGROUND: Preventive chemotherapy with donated anthelminthic drugs is the cornerstone for the control of helminthiases. However, reinfection can occur rapidly in the absence of clean water and sanit
Molecular characterization, toxin detection and resistance testing of human clinical <em>Clostridium difficile </em>isolates from Lebanon (Publications)
Clostridium (Clostridioides) difficile is the main cause for nosocomial diarrhoea in industrialised nations. Epidemiologic data on the pathogen's occurrence in other world regions are still scarce. In
Autofluorescence microscopy for paired-matched morphological and molecular identification of individual chigger mites (Acari: Trombiculidae), the... (Publications)
BACKGROUND: Conventional gold standard characterization of chigger mites involves chemical preparation procedures (i.e. specimen clearing) for visualization of morphological features, which however co
Genetic regulation of<em> IL1RL1</em> methylation and IL1RL1-a protein levels in asthma (Publications)
Interleukin-1 receptor-like 1 (IL1RL1) is an important asthma gene. (Epi)genetic regulation of IL1RL1 protein expression has not been established. We assessed the association between IL1RL1 single nuc
