Discovery of dual function acridones as a new antimalarial chemotype (Publications)
Preventing and delaying the emergence of drug resistance is an essential goal of antimalarial drug development. Monotherapy and highly mutable drug targets have each facilitated resistance, and both a
Synthesis and structure-activity relationships of new quinolone-type molecules against <em>Trypanosoma brucei</em> (Publications)
Human African trypanosomiasis (HAT) or sleeping sickness is caused by two subspecies of Trypanosoma brucei , Trypanosoma brucei gambiense , and Trypanosoma brucei rhodesiense and is one of Africa's ol
Consistently high estimates for the proportion of human exposure to malaria vector populations occurring indoors in rural Africa (Publications)
BACKGROUND: Insecticide-treated nets (ITNs) and indoor residual spraying (IRS) are highly effective tools for controlling malaria transmission in Africa because the most important vectors, from the An