Histone methyltransferase inhibitors are orally bioavailable, fast acting molecules with activity against different species causing malaria in humans (Publications)
Current antimalarials are under continuous threat due to the relentless development of drug resistance by malaria parasites. We previously reported promising in vitro parasite killing activity with th
Evaluation of banked urine samples for the detection of circulating anodic and cathodic antigens in <em>Schistosoma mekongi </em>and <em>S. japonicum... (Publications)
In Asia, Schistosoma japonicum is the predominant schistosome species, while Schistosoma mekongi is confined to limited foci in Cambodia and Lao People's Democratic Republic. While the People's Republ
Increased regulatory T-cell numbers are associated with farm milk exposure and lower atopic sensitization and asthma in childhood (Publications)
BACKGROUND: European cross-sectional studies have suggested that prenatal and postnatal farm exposure decreases the risk of allergic diseases in childhood. Underlying immunologic mechanisms are still
Exposure to environmental microorganisms and childhood asthma (Publications)
BACKGROUND: Children who grow up in environments that afford them a wide range of microbial exposures, such as traditional farms, are protected from childhood asthma and atopy. In previous studies, ma
Epidemiology of <em>Strongyloides stercoralis</em> on Mekong Islands in Southern Laos (Publications)
Strongyloides stercoralis is a neglected helminth infection potentially leading to a systemic infection in immunocompromised individuals. In Lao People's Democratic Republic (Lao PDR, Laos), informati
Acquisition of antibodies against <em>Plasmodium falciparum</em> merozoites and malaria immunity in young children: influence of age, force of... (Publications)
Individuals in Plasmodium falciparum endemic areas develop immunity to malaria after repeated exposure. Knowledge of the acquisition and nature of protective immune responses against P. falciparum is
