Comparative efficacy of Vector Guard® to Olyset® Plus insecticide-treated nets against strongly pyrethroid-resistant <em>Anopheles arabiensis</em> in... (Publications)
Introduction: The resistance of malaria vectors to pyrethroids has compromised the efficacy of pyrethroid insecticide-treated nets (ITNs). In response, ITNs with pyrethroids and piperonyl butoxide (PB
How do monomorphic bacteria evolve? The <em>Mycobacterium tuberculosis</em> complex and the awkward population genetics of extreme clonality (Publications)
Exchange of genetic material through sexual reproduction or horizontal gene transfer is ubiquitous in nature. Among the few outliers that rarely recombine and mainly evolve by de novo mutation are a g
Eastern Africa, Madagascar and Indian Ocean Islands (Publications)
Travellers in East Africa are potentially exposed to malaria, arboviral infections, schistosomiasis, African sleeping sickness (African trypanosomiasis) and many other infectious diseases. Exposure de
Characterizing the pharmacological interaction of the antimalarial combination artefenomel-piperaquine in healthy volunteers with induced blood-stage... (Publications)
BACKGROUND: The combination antimalarial artefenomel-piperaquine failed to achieve target efficacy in a phase 2b study in Africa and Vietnam. We retrospectively evaluated whether characterizing the ph
A study protocol for a multi-country cluster randomized controlled trial of the impact of a multi-component One Health strategy to eliminate... (Publications)
BACKGROUND: Opisthorchis viverrini (OV) and soil-transmitted helminths (STH) are two of the most common helminths contributing to the Neglected Tropical Disease (NTDs) burden in the Lower Mekong Basin
Seeking and receiving hypertension and diabetes mellitus care in Tanzania (Publications)
The rapid increase in chronic non-communicable diseases (NCDs) poses a major challenge to already strained health systems in sub-Saharan Africa. This study investigates the factors associated with see