Perceptions of roles of community healthcare workers in early childhood in Limpopo, South Africa (Publications)
BACKGROUND: As part of the Reengineering Primary Health Care initiative, the South African National Department of Health (NDoH) has committed to expanding access to home-based care provided by communi
Participation in organised sports and longitudinal development of physical activity in Swiss youth: the population-based SOPHYA cohort (Publications)
BACKGROUND: Maintaining physical activity throughout life is crucial for overall health and wellbeing. Yet the age-related decline in average physical activity, a natural phenomenon also observed in a
Pharmacometric analysis to describe pharmacokinetics and exposure-efficacy response of ivermectin in adolescents infected with <em>Trichuris... (Publications)
The efficacy of the combination therapy of albendazole and ivermectin against Trichuris trichiura infection is higher in Tanzania than in Côte d'Ivoire. This study therefore aimed to investigate the d
Feasibility and acceptability of the Problem Management for Moms programme for improving maternal mental health in Zambia: an open-label trial (Publications)
BACKGROUND: Psychological distress is common among mothers in low-income and middle-income countries, limiting their capacity to care for themselves and their children. This study aimed to test the fe
Total synthesis of tosyl-samroiyotmycin A and its biological profiling (Publications)
A total synthesis of the enantiopure syn,syn-tosyl-samroiyotmycin A, a C2-symmetric 20-membered antimalarial macrodiolide with syn,syn-configuration of the 8,24-dihydroxy-9,25-dimethyl units and it's
Medium-ring keto bislactams with antischistosomal activity (Publications)
We discovered medium-ring keto bislactams as a new antischistosomal chemotype. The ketone functional group and isoindolinone substructure were required for high antischistosomal activity. Aryl substit
Rapid increase in the risk of heat-related mortality (Publications)
Heat-related mortality has been identified as one of the key climate extremes posing a risk to human health. Current research focuses largely on how heat mortality increases with mean global temperatu
Malaria rapid tests, febrile illness management, and child mortality across sub-Saharan African countries (Publications)
IMPORTANCE: A prompt malaria diagnosis is crucial for the management of children with febrile illness in sub-Saharan African countries, where malaria remains a leading cause of mortality among childre
