The haemochromatosis gene Hfe and Kupffer cells control LDL cholesterol homeostasis and impact on atherosclerosis development (Publications)
AIMS: Imbalances of iron metabolism have been linked to the development of atherosclerosis. However, subjects with hereditary haemochromatosis have a lower prevalence of cardiovascular disease. The ai
Correlates and outcomes of posttransplant smoking in solid organ transplant recipients: a systematic literature review and meta-analysis (Publications)
BACKGROUND: Despite smoking being an absolute or relative contraindication for transplantation, about 11-40% of all patients continue or resume smoking posttransplant. This systematic review with meta
The good clinical practice guideline and its interpretation - perceptions of clinical trial teams in sub-Saharan Africa (Publications)
OBJECTIVES: To explore the advantages and challenges of working with the Good Clinical Practice (GCP)-International Conference of Harmonization (ICH) E6 guideline and its interpretation from the persp
Why do marital partners of people living with HIV not test for HIV? A qualitative study in Lusaka, Zambia (Publications)
BACKGROUND: Knowledge of HIV status is crucial for HIV prevention and management in marital relationships. Yet some marital partners of people living with HIV decline HIV testing despite knowing the H
Spatio-temporal distribution of <em>Mycobacterium tuberculosis</em> complex strains in Ghana (Publications)
BACKGROUND: There is a perception that genomic differences in the species/lineages of the nine species making the Mycobacterium tuberculosis complex (MTBC) may affect the efficacy of distinct control
Discovery of a mosaic-like biosynthetic assembly line with a decarboxylative off-loading mechanism through a combination of genome mining and imaging (Publications)
The biosynthetic gene cluster for the antiplasmodial natural product siphonazole was identified by using a combination of genome mining, imaging, and expression studies in the natural producer Herpeto
Evaluation of a urine pooling strategy for the rapid and cost-efficient prevalence classification of schistosomiasis (Publications)
BACKGROUND: A key epidemiologic feature of schistosomiasis is its focal distribution, which has important implications for the spatial targeting of preventive chemotherapy programs. We evaluated the d
Analysis of diagnostic findings from the European mobile laboratory in Gueckedou, Guinea, March 2014 through March 2015 (Publications)
BACKGROUND: A unit of the European Mobile Laboratory (EMLab) consortium was deployed to the Ebola virus disease (EVD) treatment unit in Gueckedou, Guinea, from March 2014 through March 2015. METHODS:
