A comparative study of the efficacies of chloroquine and a pyrimethamine-dapsone combination in clearing <em>Plasmodium falciparum</em> parasitaemia... (Publications)
A randomized study on the in vivo efficacies of chloroquine and a pyrimethamine-dapsone combination (Maloprim) in clearing P. falciparum parasitaemia was carried out in 77 asymptomatic semi-immune sch
Immunogenicity and adverse effects of inactivated virosome versus alum-adsorbed hepatitis A vaccine: a randomized controlled trial (Publications)
Immunogenicity and adverse effects of a novel inactivated hepatitis A vaccine based on virosomes (IRIV-HAV) was compared with a standard vaccine adsorbed to aluminium (Al-HAV). Seronegative volunteers
Nifurtimox-eflornithine combination therapy for second-stage <em>Trypanosoma brucei gambiense</em> sleeping sickness: a randomized clinical trial in... (Publications)
BACKGROUND: Human African trypanosomiasis caused by Trypanosoma brucei gambiense is a fatal disease. Current treatment options for patients with second-stage disease are either highly toxic or impract
Synthesis and antiparasitic evaluation of bis-2,5-[4-guanidinophenyl]thiophenes (Publications)
A series of bis-2,5-[4-guanidinophenyl]thiophenes were prepared in a five step process starting from 2,5-bis[trimethylstannyl]thiophene. The compounds were evaluated in vitro against Trypanosoma bruce
Dicationic biphenyl benzimidazole derivatives as antiprotozoal agents (Publications)
A series of biphenyl benzimidazoles diamidines 6a-i were synthesized from their respective diamidoximes, through the bis-O-acetoxyamidoxime followed by hydrogenation in glacial acetic acid/ethanol in
