Consensus numbering system for the rifampicin resistance-associated rpoB gene mutations in pathogenic mycobacteria (Publications)
The rpoB gene codes for the RNA polymerase beta subunit, which is the target of rifampicin, an essential drug in the treatment of tuberculosis and other mycobacterial infections. This gene is present
Bacterial microbiota of the upper respiratory tract and childhood asthma (Publications)
BACKGROUND: Patients with asthma and healthy controls differ in bacterial colonization of the respiratory tract. The upper airways have been shown to reflect colonization of the lower airways, the act
Cyclombandakamines A1 and A2, oxygen-bridged naphthylisoquinoline dimers from a Congolese <em>Ancistrocladus liana</em> (Publications)
Cyclombandakamines A1 (1) and A2 (2), both with an unprecedented pyrane-cyclohexenone-dihydrofuran sequence and six stereocenters and two chiral axes, are the first oxygen-bridged dimeric naphthylisoq
Dioncophyllines C2, D2, and F and related naphthylisoquinoline alkaloids from the Congolese liana <em>Ancistrocladus ileboensis</em> with potent... (Publications)
Dioncophylline F (1), the first 5,8'-coupled dioncophyllaceous alkaloid (i.e., lacking an oxygen function at C-6 and possessing an R-configuration at C-3), was isolated from the recently described Con
Antiprotozoal activity-based profiling of a dichloromethane extract from <em>Anthemis nobilis</em> flowers (Publications)
A dichlomethane extract of Anthemis nobilis flower cones showed promising in vitro antiprotozoal activity against Trypanosoma brucei rhodesiense and Leishmania donovani, with IC50 values of 1.43 +/- 0
Decentralization of health systems in low and middle income countries: a systematic review (Publications)
OBJECTIVES: A substantial number of low and middle income countries (LMICs) have implemented health sector reforms in the last 40 years, and the majority of them have included some degree of decentral
Actual and perceived weight status and its association with slimming and energy-balance related behaviours in 10- to 12-year-old European children:... (Publications)
BACKGROUND: Both parents' and children's perception of children's weight status may be important predictors of slimming and energy-balance related behaviours, independent of children's actual weight s
The effects of growing up on a farm on adult lung function and allergic phenotypes: an international population-based study (Publications)
RATIONALE: Evidence has suggested that exposure to environmental or microbial biodiversity in early life may impact subsequent lung function and allergic disease risk. OBJECTIVES: To investigate the i