Preclinical evaluation of the antifolate QN254, 5-chloro- N'6'-(2,5-dimethoxy-benzyl)-quinazoline-2,4,6-triamine, as an antimalarial drug... (Publications)
Drug resistance against dihydrofolate reductase (DHFR) inhibitors-such as pyrimethamine (PM)-has now spread to almost all regions where malaria is endemic, rendering antifolate-based malaria treatment
Efficacy of killed whole-parasite vaccines in the prevention of leishmaniasis: a meta-analysis (Publications)
Despite decades of investigation in countries on three continents, an efficacious vaccine against Leishmania infections has not been developed. Although some indication of protection was observed in s
Efficacy of the cyclooctadepsipeptide PF1022A against <em>Heligmosomoides bakeri in vitro</em> and <em>in vivo</em> (Publications)
SUMMARYThe cyclooctadepsipeptide PF1022A derived from the fungus, Mycelia sterilia, is characterized by a broad spectrum of activity against different parasitic gastrointestinal nematodes of livestock
Pulmonary schistosomiasis - imaging features (Publications)
Schistosomiasis is a helminthic infection that is endemic in tropical and subtropical regions. Pulmonary involvement can be divided into two categories: acute or chronic compromise. Chronic and recurr
Sushi delights and parasites: the risk of fishborne and foodborne parasitic zoonoses in Asia (Publications)
Because of the worldwide popularization of Japanese cuisine, the traditional Japanese fish dishes sushi and sashimi that are served in Japanese restaurants and sushi bars have been suspected of causin
Imported strongyloidosis: a longitudinal analysis of 31 cases (Publications)
BACKGROUND: Attention regarding imported tropical diseases is typically focused on malaria, although other parasitic diseases such as strongyloidosis may also cause serious health problems. The import
