Antitrypanosomal isothiocyanate and thiocarbamate glycosides from <em>Moringa peregrina </em>[Letter] (Publications)
O-Methyl (1), O-ethyl (2), and O-butyl (3) 4-[(alpha-L-rhamnosyloxy) benzyl] thiocarbamate (E), along with 4-(alpha-L-rhamnosyloxy) benzyl isothiocyanate (4) have been isolated from the aerial parts o
A genetic variation in the adenosine A2A receptor gene (ADORA2A) contributes to individual sensitivity to caffeine effects on sleep (Publications)
Caffeine is the most widely used stimulant in Western countries. Some people voluntarily reduce caffeine consumption because it impairs the quality of their sleep. Studies in mice revealed that the di
Novel 3-nitro-1H-1,2,4-triazole-based compounds as potential anti-Chagasic drugs: <em>in vivo</em> studies (Publications)
Background: Chagas disease is caused by the parasite Trypanosoma cruzi, is endemic in Latin America and leads to an estimated 14,000 deaths per year and around 100 million people at risk of infection.
Air pollution and childhood leukaemia: a nationwide case-control study in Italy (Publications)
OBJECTIVES: Leukaemia is the most common cancer in children, but its aetiology is still poorly understood. We tested the hypothesis that traffic-related air pollution is associated with paediatric leu
Adenosinergic mechanisms contribute to individual differences in sleep deprivation-induced changes in neurobehavioral function and brain rhythmic... (Publications)
Large individual differences characterize the changes induced by sleep deprivation on neurobehavioral functions and rhythmic brain activity. To investigate adenosinergic mechanisms in these difference
Feeding behaviour of tsetse flies infected with <em>salivarian trypanosomes</em> (Publications)
Although much is known about factors which determine infection rates of salivarian trypanosomes (subgenera Nannomonas, Duttonella and Tryanozoon) in the tsetse fly Glossina, it is not clear why infect
<em>In vitro</em> and <em>in vivo</em> activity of the chloroaryl-substituted imidazole viniconazole against <em>Trypanosoma cruzi</em> (Publications)
Chagas disease (CD) is caused by the intracellular protozoan parasite Trypanosoma cruzi and affects more than 10 million people in poor areas of Latin America. There is an urgent need for alternative
Consequences of genomic diversity in <em>Mycobacterium tuberculosis</em> (Publications)
The causative agent of human tuberculosis, Mycobacterium tuberculosis complex (MTBC), comprises seven phylogenetically distinct lineages associated with different geographical regions. Here we review
