The effect of malaria control on <em>Plasmodium falciparum</em> in Africa between 2000 and 2015 (Publications)
Since the year 2000, a concerted campaign against malaria has led to unprecedented levels of intervention coverage across sub-Saharan Africa. Understanding the effect of this control effort is vital t
Blood or urine IP-10 cannot discriminate between active tuberculosis and respiratory diseases different from tuberculosis in children (Publications)
OBJECTIVES: Interferon-? inducible protein 10 (IP-10), either in blood or in urine, has been proposed as a tuberculosis (TB) biomarker for adults. This study aims to evaluate the potential of IP-10 di
RFX transcription factors are essential for hearing in mice (Publications)
Sensorineural hearing loss is a common and currently irreversible disorder, because mammalian hair cells (HCs) do not regenerate and current stem cell and gene delivery protocols result only in immatu
Predominance of <em>dfrG</em> as determinant of trimethoprim resistance in imported <em>Staphylococcus aureus</em> (Publications)
To investigate the global occurrence of trimethoprim-sulfamethoxazole resistance and the genetic mechanisms of trimethoprim resistance, we analysed Staphylococcus aureus from travel-associated skin an
Structure elucidation and activity of kolossin A, the D-/L-pentadecapeptide product of a giant nonribosomal peptide synthetase (Publications)
The largest continuous bacterial nonribosomal peptide synthetase discovered so far is described. It consists of 15 consecutive modules arising from an uninterrupted, fully functional gene in the entom
Molecular and culture-based diagnosis of <em>Clostridium difficile</em> isolates from Côte d'Ivoire after prolonged storage at disrupted cold chain... (Publications)
BACKGROUND: Although Clostridium difficile is a major cause of diarrhoea, its epidemiology in tropical settings is poorly understood. Strain characterisation requires work-up in specialised laboratori
The association of air pollution and depressed mood in 70,928 individuals from four European cohorts (Publications)
BACKGROUND: Exposure to ambient air pollution may be associated with impaired mental health, including depression. However, evidence originates mainly from animal studies and epidemiological studies i
Geographical and temporal structures of <em>Legionella pneumophila</em> sequence types in Comunitat Valenciana (Spain), 1998 to 2013 (Publications)
Legionella pneumophila is an accidental human pathogen associated with aerosol formation in water-related sources. High recombination rates make Legionella populations genetically diverse, and nearly