Biobanking across the phenome - at the center of chronic disease research (Publications)
BACKGROUND: Recognized public health relevant risk factors such as obesity, physical inactivity, smoking or air pollution are common to many non-communicable diseases (NCDs). NCDs cluster and co-morbi
Air pollution and diabetes association: modification by type 2 diabetes genetic risk score (Publications)
Exposure to ambient air pollution (AP) exposure has been linked to type 2 diabetes (T2D) risk. Evidence on the impact of T2D genetic variants on AP susceptibility is lacking. Compared to single varian
Differences in indoor versus outdoor concentrations of ultrafine particles, PM2.5, PMabsorbance and NO2 in Swiss homes (Publications)
Indoor air quality is a growing concern as we spend the majority of time indoors and as new buildings are increasingly airtight for energy saving purposes. For a better understanding of residential in
Spatial variation of PM elemental compositon between and within 20 European study areas - results of the ESCAPE project (Publications)
An increasing number of epidemiological studies suggest that adverse health effects of air pollution may be related to particulate matter (PM) composition, particularly trace metals. However, we lack
Serum bilirubin is associated with lung function in a Swiss general population sample (Publications)
Bilirubin is a strong antioxidant. Increased serum levels were associated with respiratory disease and mortality risk. We studied the association of bilirubin with lung function in the SAPALDIA cohort
Sixteen new lung function signals identified through 1000 Genomes Project reference panel imputation (Publications)
Lung function measures are used in the diagnosis of chronic obstructive pulmonary disease. In 38,199 European ancestry individuals, we studied genome-wide association of forced expiratory volume in 1
40 years of progress in female cancer death risk: a Bayesian spatio-temporal mapping analysis in Switzerland (Publications)
BACKGROUND: In the past decades, mortality of female gender related cancers declined in Switzerland and other developed countries. Differences in the decrease and in spatial patterns within Switzerlan
Association between tuberculosis, diabetes and 25 hydroxyvitamin D in Tanzania: a longitudinal case control study (Publications)
BACKGROUND: Vitamin D level is inversely associated with tuberculosis (TB) and diabetes (DM). Vitamin D could be a mediator in the association between TB and DM. We examined the associations between v
Disease, activity and schoolchildren's health (DASH) in Port Elizabeth, South Africa: a study protocol (Publications)
BACKGROUND: An in-depth epidemiological investigation on intestinal parasite infections in an impoverished area of Port Elizabeth, South Africa provides a unique opportunity for research on its impact
Menopause is associated with accelerated lung function decline (Publications)
RATIONALE: Menopause is associated with changes in sex hormones, which affect immunity, inflammation, and osteoporosis and may impair lung function. Lung function decline has not previously been inves
