Ferrocenyl derivatives of the anthelmintic praziquantel: design, synthesis and biological evaluation (Publications)
The design, synthesis and biological evaluation of eighteen ferrocenyl derivatives (4A-12A and 4B-12B) of the most-well known drug against schistosomiasis, namely praziquantel (PZQ), are reported. The
Cultural epidemiology of neurasthenia spectrum disorders in four general hospital outpatient clinics of urban Pune, India (Publications)
Disorders emphasizing symptoms of fatigue and/or weakness, collectively termed Neurasthenia Spectrum Disorders (NSDs), typically emphasize a biological basis in the West and social origins in East Asi
Cord blood allergen-specific IgE is associated with reduced IFN-gamma production by cord blood cells: The Protection against Allergy-Study in Rural... (Publications)
BACKGROUND: It is currently discussed whether allergic sensitization may start in utero under the influence of the maternal immune system and environmental determinants. OBJECTIVE: To investigate the
PTEN expression is a strong predictor of survival in mesothelioma patients (Publications)
BACKGROUND: Malignant pleural mesothelioma (MPM) is a highly aggressive tumour with poor prognosis and limited response to therapy. MPM is characterised by complex chromosomal aberrations, including c
A community-randomized evaluation of the effect of intermittent preventive treatment in infants on antimalarial drug resistance in southern Tanzania (Publications)
Background: Intermittent Preventive Treatment in infants (IPTi) is the administration of sulphadoxine-pyrimethamine (SP) at 2, 3 and 9 months of age to prevent malaria. We investigated the influence o
One-hour rule-out and rule-in of acute myocardial infarction using high-sensitivity cardiac troponin T (Publications)
BACKGROUND High-sensitivity cardiac troponin (hs-cTn) assays seem to improve the early diagnosis of acute myocardial infarction (AMI), but it is unknown how to best use them in clinical practice. Our
Quantitative assessment of eosinophiluria in <em>Schistosoma haematobium</em> infections: a new marker of infection and bladder morbidity (Publications)
Eosinophiluria, as quantified by measuring eosinophil cationic protein (ECP) in urinary extracts, microhematuria, egg excretion, and ultrasound-detectable bladder pathology were recorded in Schistosom
Meat preparation and colorectal adenomas in a large sigmoidoscopy-based case-control study in California (United States) (Publications)
The often observed association between red meat and colorectal cancer could be due in part to mutagens, such as heterocyclic amines (HCA), that are present in cooked meat. HCAs are highly mutagenic an
