Evaluation of methods for modeling transcription factor sequence specificity (Publications)
Genomic analyses often involve scanning for potential transcription factor (TF) binding sites using models of the sequence specificity of DNA binding proteins. Many approaches have been developed to m
In vitro and in vivo activities of synthetic trioxolanes against major human schistosome species (Publications)
Schistosomiasis is a parasitic disease that remains of considerable public health significance in tropical and subtropical environments. Since the mainstay of schistosomiasis control is chemotherapy w
Artemether administered together with hemin damages schistosomes in vitro (Publications)
We conducted experiments in vitro to assess the effect of artemether in combination with haemin on adult Schistosoma japonicum, S. mansoni and S. haematobium. When schistosomes were maintained in a me
Evaluation of the "future non-smokers" campaign of the Swiss Society of Pharmacists (Publications)
In order to promote low threshold smoking cessation, a campaign was organized by the Swiss Society of Pharmacists in 616 Swiss pharmacies. The evaluation of this project took into consideration the ac
Screening for mutations related to atovaquone/proguanil resistance in treatment failures and other imported isolates of <em>Plasmodium falciparum</em>... (Publications)
BACKGROUND: Two single-point mutations of the Plasmodium falciparum cytochrome b gene (Tyr268Asn and Tyr268Ser) were recently reported in cases of atovaquone/proguanil (Malarone) treatment failure. Ho
