Out-of-pocket expenditures for primary health care in Tajikistan: a time-trend analysis (Publications)
BACKGROUND: Aligned with the international call for universal coverage of affordable and quality health care, the government of Tajikistan is undertaking reforms of its health system aiming amongst ot
Rapid urban malaria appraisal (RUMA) IV: epidemiology of urban malaria in Cotonou (Benin) (Publications)
BACKGROUND: An estimated 40 % of the population in Benin lives in urban areas. The purpose of the study was to estimate malaria endemicity and the fraction of malaria-attributable fevers in health fac
Naphthoquinone derivatives exert their antitrypanosomal activity via a multi-target mechanism (Publications)
BACKGROUND AND METHODOLOGY: Recently, we reported on a new class of naphthoquinone derivatives showing a promising anti-trypanosomatid profile in cell-based experiments. The lead of this series (B6, 2
Community-based surveillance of malaria vector larval habitats: a baseline study in urban Dar es Salaam, Tanzania (Publications)
ABSTRACT: BACKGROUND: As the population of Africa rapidly urbanizes it may be possible to protect large populations from malaria by controlling aquatic stages of mosquitoes. Here we present a baseline
Sero-epidemiology as a tool to screen populations for exposure to <em>Mycobacterium ulcerans</em> (Publications)
BACKGROUND: Previous analyses of sera from a limited number of Ghanaian Buruli ulcer (BU) patients, their household contacts, individuals living in BU non-endemic regions as well as European controls
Air pollution and atherosclerosis: new evidence to support air quality policies (Publications)
Nino Künzli discusses a large new cohort study that provides some of the first human evidence for the impact of air pollution on the development of atherosclerosis.
Activity of oxantel pamoate monotherapy and combination chemotherapy against <em>Trichuris muris</em> and hookworms: revival of an old drug (Publications)
BACKGROUND: It is widely recognized that only a handful of drugs are available against soil-transmitted helminthiasis, all of which are characterized by a low efficacy against Trichuris trichiura, whe
A new double-antibody sandwich ELISA targeting <em>Plasmodium falciparum</em> aldolase to evaluate anti-malarial drug sensitivity (Publications)
BACKGROUND: The standard in vitro test to assess anti-malarial activity of chemical compounds is the [3H]hypoxanthine incorporation assay. It is a radioactivity-based method to measure DNA replication
