dUTPase as a platform for antimalarial drug design: structural basis for the selectivity of a class of nucleoside inhibitors (Publications)
Pyrimidine metabolism is a major route for therapeutic intervention against malaria. Here we report inhibition and structural studies on the deoxyuridine nucleotidohydrolase from the malaria parasite
Identification of fecal input sites in spring water by selection and genotyping of multiresistant <em>Escherichia coli</em> (Publications)
The localization of fecal input sites is important for water quality management. For this purpose, we have developed a new approach based on a three-step procedure, including a preparatory phase, the
Determining soil-transmitted helminth infection status and physical fitness of school-aged children (Publications)
Soil-transmitted helminth (STH) infections are common. Indeed, more than 1 billion people are affected, mainly in the developing world where poverty prevails and hygiene behavior, water supply, and sa
A potential impact of climate change and water resource development on the transmission of <em>Schistosoma japonicum</em> in China (Publications)
There is growing consensus among climate modellers that the unusual global warming observed in the last decades of the 20th century is primarily forced by human activities, namely greenhouse gas incre
Potential impact of climate change on schistosomiasis transmission in China (Publications)
Appraisal of the present and future impact of climate change and climate variability on the transmission of infectious diseases is a complex but pressing public health issue. We developed a biology-dr
A Bayesian-based approach for spatio-temporal modeling of county level prevalence of <em>Schistosoma japonicum</em> infection in Jiangsu province,... (Publications)
Spatio-temporal variations of Schistosoma japonicum infection risk in Jiangsu province, China, were examined and the relationships between key climatic factors and infection prevalence at the county l
