An in-depth analysis of a piece of shit: distribution of <em>Schistosoma mansoni</em> and hookworm eggs in human stool (Publications)
BACKGROUND: An accurate diagnosis of helminth infection is important to improve patient management. However, there is considerable intra- and inter-specimen variation of helminth egg counts in human f
Assessment of global reporting of adverse drug reactions for anti-malarials, including artemisinin-based combination therapy, to the WHO Programme for... (Publications)
BACKGROUND: In spite of enhanced control efforts, malaria remains a major public health problem causing close to a million deaths annually. With support from several donors, large amounts of artemisin
Clinical presentation of <em>T.b. rhodesiense</em> sleeping sickness in second stage patients from Tanzania and Uganda (Publications)
BACKGROUND: A wide spectrum of disease severity has been described for Human African Trypanosomiasis (HAT) due to Trypanosoma brucei rhodesiense (T.b. rhodesiense), ranging from chronic disease patter
Increased use of malaria rapid diagnostic tests improves targeting of anti-malarial treatment in rural Tanzania: implications for nationwide rollout... (Publications)
BACKGROUND: The World Health Organization recommends parasitological confirmation of all malaria cases. Tanzania is implementing a phased rollout of malaria rapid diagnostic tests (RDTs) for routine u
Anti-protozoal activity of aporphine and protoberberine alkaloids from <em>Annickia kummeriae</em> (Engl. & Diels) Setten & Maas (Annonaceae) (Publications)
BACKGROUND: Malaria, trypanosomiasis and leishmaniasis have an overwhelming impact in the poorest countries in the world due to their prevalence, virulence and drug resistance ability. Currently, ther
The usefulness of twenty-four molecular markers in predicting treatment outcome with combination therapy of amodiaquine plus... (Publications)
BACKGROUND: In Papua New Guinea (PNG), combination therapy with amodiaquine (AQ) or chloroquine (CQ) plus sulphadoxine-pyrimethamine (SP) was introduced as first-line treatment against uncomplicated m
Serological evaluation of <em>Mycobacterium ulcerans</em> antigens identified by comparative genomics (Publications)
A specific and sensitive serodiagnostic test for Mycobacterium ulcerans infection would greatly assist the diagnosis of Buruli ulcer and would also facilitate seroepidemiological surveys. By comparati
Influence of a lifestyle intervention in preschool children on physiological and psychological parameters (Ballabeina): study design of a cluster... (Publications)
BACKGROUND: Childhood obesity and physical inactivity are increasing dramatically worldwide. Children of low socioeconomic status and/or children of migrant background are especially at risk. In gener
