Balgacyclamides, antiplasmodial heterocyclic peptides from <em>Microcystis aeruguinosa</em> EAWAG 251 (Publications)
The isolation and structural characterization of three new heterocyclic and macrocyclic peptides, balgacyclamides A-C, from Microcystis aeruginosa EAWAG 251 are reported. The constitutions were determ
A molecular marker of artemisinin-resistant <em>Plasmodium falciparum</em> malaria (Publications)
Plasmodium falciparum resistance to artemisinin derivatives in southeast Asia threatens malaria control and elimination activities worldwide. To monitor the spread of artemisinin resistance, a molecul
Men benefit more from midlife leisure-time physical activity than women regarding the development of late-life disability - results from the KORA-age... (Publications)
OBJECTIVE: Encouraging physical activity is an important public health measure to reduce disability prevalence in the aged. The aims of this study were to determine the association between midlife phy
Structure and biosynthesis of xenoamicins from entomopathogenic <em>Xenorhabdus</em> (Publications)
During the search for novel natural products from entomopathogenic Xenorhabdus doucetiae DSM17909 and X. mauleonii DSM17908 novel peptides named xenoamicins were identified in addition to the already
Asthma during pregnancy and clinical outcomes in offspring: a national cohort study (Publications)
BACKGROUND AND OBJECTIVE: Maternal asthma is a common pregnancy complication, with adverse short-term effects for the offspring. The objective was to determine whether asthma during pregnancy is a ris
Random number generation during sleep deprivation: effects of caffeine on response maintenance and stereotypy (Publications)
Neurophysiological and functional imaging studies have demonstrated that frontal regions of the brain are particularly responsive to homeostatic sleep pressure. Previous neuropsychological studies ind
IV thrombolysis and renal function (Publications)
OBJECTIVE: To investigate the association of renal impairment on functional outcome and complications in stroke patients treated with IV thrombolysis (IVT). METHODS: In this observational study, we co
Cross-reactive immune response elicited by parenteral Vi polysaccharide typhoid vaccine against non-typhoid <em>Salmonellae</em> (Publications)
BACKGROUND: Despite 155000 deaths and over 90 million cases - and the current emergence of antimicrobial resistance - no vaccines are available against non-typhoid Salmonellae (NTS). We recently prese
Targeting <em>Plasmodium</em> PI(4)K to eliminate malaria (Publications)
Achieving the goal of malaria elimination will depend on targeting Plasmodium pathways essential across all life stages. Here we identify a lipid kinase, phosphatidylinositol-4-OH kinase (PI(4)K), as
