Exogenous iron increases fasciocidal activity and hepatocellular toxicity of the synthetic endoperoxides OZ78 and MT04 (Publications)
The synthetic peroxides OZ78 and MT04 recently emerged as fasciocidal drug candidates. However, the effect of iron on fasciocidal activity and hepatocellular toxicity of these compounds is unknown. We
Reasons for prehospital delay in acute ischemic stroke (Publications)
Background Prehospital delay reduces the proportion of patients with stroke treated with recanalization therapies. We aimed to identify novel and modifiable risk factors for prehospital delay. Methods
Neglected tropical diseases in the People's Republic of China: progress towards elimination (Publications)
Since the founding of the People's Republic of China in 1949, considerable progress has been made in the control and elimination of the country's initial set of 11 neglected tropical diseases. Indeed,
Antiprotozoal and antihelminthic properties of plants ingested by wild Japanese macaques (<em>Macaca fuscata yakui</em>) in Yakushima Island (Publications)
ETHNOPHARMACOLOGICAL RELEVANCE: Primates forage on a variety of plant parts to balance their dietary intake to meet requirements of energy, nutrition and maintenance, however the reason(s) leading the
Spatial effects of permethrin-impregnated bed nets on child mortality: 26 years on, a spatial reanalysis of a cluster randomized trial (Publications)
In addition to the direct effect of insecticide-treated nets (ITNs), there has been evidence for spatial indirect effects. Spatial analyses in cluster randomized trials (CRTs) are rare, but a large-sc
Mapping routine malaria incidence at village level for targeted control in Papua New Guinea (Publications)
Malaria surveillance and response-systems are essential for identifying the areas most affected by malaria and for targeting interventions and optimising resources. This study aimed to assess whether
Atopy modifies the association between inhaled corticosteroid use and lung function decline in patients with asthma (Publications)
BACKGROUND: Inhaled corticosteroids (ICSs) are the mainstay of asthma treatment, but response to medication is variable. Patients with allergic inflammation generally show a better short-term response
Non-randomized studies using causal-modelling may give different answers than RCTs: a meta-epidemiological study (Publications)
OBJECTIVES: To evaluate how estimated treatment effects agree between non-randomized studies using causal modelling with marginal structural models (MSM-studies) and randomized trials (RCTs). STUDY DE
