Peroxide bond-dependent antiplasmodial specificity of artemisinin and OZ277 (RBx11160) (Publications)
Using nonperoxidic analogs of artemisinin and OZ277 (RBx11160), the strong in vitro antiplasmodial activities of the latter two compounds were shown to be peroxide bond dependent. In contrast, the wea
Association between annoyance and individuals' values of nitrogen dioxide in a European setting (Publications)
INTRODUCTION: Annoyance caused by air pollution has been proposed as an indicator of exposure to air pollution. The aim of this study was to assess the geographical homogeneity of the relationship bet
Associations of daily walking activity with biomarkers related to cardiac distress in patients with chronic obstructive pulmonary disease (Publications)
Background: The prevalence of cardiovascular mortality is high in Chronic Obstructive Pulmonary Disease (COPD) and the identification of clinical parameters to improve risk stratification is of great
Imported falciparum malaria in Europe: sentinel surveillance data from the European network on surveillance of imported infectious diseases (Publications)
Malaria continues to have a high morbidity rate associated among European travelers. Thorough recording of epidemiological and clinical aspects of imported malaria has been helpful in the detection of
Synthesis and antiprotozoal activity of aza-analogues of furamidine (Publications)
6-[5-(4-Amidinophenyl)furan-2-yl]nicotinamidine (8a) was synthesized from 6-[5-(4-cyanophenyl)furan-2-yl]nicotinonitrile (4a), through the bis-O-acetoxyamidoxime followed by hydrogenation. Compound 4a
Pharmacokinetic parameters of artesunate and dihydroartemisinin in rats infected with <em>Fasciola hepatica</em> (Publications)
OBJECTIVES: The pharmacokinetic (PK) parameters of artesunate, recently discovered to possess promising trematocidal activity, and its main metabolite dihydroartemisinin (DHA) were determined in rats