Limited efficacy of repeated praziquantel treatment in <em>Schistosoma mansoni</em> infections as revealed by highly accurate diagnostics, PCR and... (Publications)
BACKGROUND: Most studies assessing praziquantel (PZQ) efficacy have used relatively insensitive diagnostic methods, thereby overestimating cure rate (CR) and intensity reduction rate (IRR). To determi
Helminth infections: enabling the World Health Organization road map (Publications)
Helminthiases are considered among the most persistent public health problems. Control and/or elimination remains a global health challenge and the World Health Organization Road Map highlights critic
Advancing detection and response capacities for emerging and re-emerging pathogens in Africa (Publications)
Recurrent disease outbreaks caused by a range of emerging and resurging pathogens over the past decade reveal major gaps in public health preparedness, detection, and response systems in Africa. Under
Pre-referral rectal artesunate: no cure for unhealthy systems (Publications)
Pre-referral rectal artesunate suppositories can save the lives of children with severe malaria if patients receive adequate post-referral care. A multi-country randomised controlled trial reporting o
Evaluation of nanopore sequencing for <em>Mycobacterium tuberculosis </em>drug susceptibility testing and outbreak investigation: a genomic analysis (Publications)
BACKGROUND: Mycobacterium tuberculosis whole-genome sequencing (WGS) has been widely used for genotypic drug susceptibility testing (DST) and outbreak investigation. For both applications, Illumina te
Health system readiness and the implementation of rectal artesunate for severe malaria in sub-Saharan Africa: an analysis of real-world costs and... (Publications)
BACKGROUND: Rectal artesunate, an efficacious pre-referral treatment for severe malaria in children, was deployed at scale in Uganda, Nigeria, and DR Congo. In addition to distributing rectal artesuna
Urban onsite sanitation upgrades and synanthropic flies in Maputo, Mozambique: effects on enteric pathogen infection risks (Publications)
Synanthropic filth flies transport enteric pathogens from feces to food, which upon consumption poses an infection risk. We evaluated the effect of an onsite sanitation intervention horizontal line in
