Differential patterns of infection and disease with <em>P. falciparum</em> and <em>P. vivax</em> in young Papua New Guinean children (Publications)
BACKGROUND: Where P. vivax and P. falciparum occur in the same population, the peak burden of P. vivax infection and illness is often concentrated in younger age groups. Experiences from malaria thera
Multiplicity and diversity of <em>Plasmodium vivax</em> infections in a highly endemic region in Papua New Guinea (Publications)
Plasmodium vivax is highly endemic in the lowlands of Papua New Guinea and accounts for a large proportion of the malaria cases in children less than 5 years of age. We collected 2117 blood samples at
Modelling the epidemiological impact of intermittent preventive treatment against malaria in infants (Publications)
BACKGROUND: Trials of intermittent preventive treatment against malaria in infants (IPTi) using sulphadoxine-pyrimethamine (SP) have shown a positive, albeit variable, protective efficacy against clin
The unmet need for emergency obstetric care in Tanga Region, Tanzania (Publications)
ABSTRACT: BACKGROUND: Improving maternal health by reducing maternal mortality constitutes the fifth Millennium Development Goal and represents a key public health challenge in the United Republic of
Isolation of <em>Trypanosoma brucei gambiense</em> from cured and relapsed sleeping sickness patients and adaptation to laboratory mice (Publications)
BACKGROUND: Sleeping sickness due to Trypanosoma brucei (T.b.) gambiense is still a major public health problem in some central African countries. Historically, relapse rates around 5% have been obser
In-hospital safety in field conditions of nifurtimox eflornithine combination therapy (NECT) for <em>T.b. gambiense</em> sleeping sickness (Publications)
BACKGROUND: Trypanosoma brucei (T.b.) gambiense Human African trypanosomiasis (HAT; sleeping sickness) is a fatal disease. Until 2009, available treatments for 2(nd) stage HAT were complicated to use,