Substance use referral, treatment utilization, and patient costs associated with problematic substance use in people living with HIV in Cape Town,... (Publications)
INTRODUCTION: Despite efforts to detect and treat problematic substance use (SU) among people living with HIV (PLWH) in South Africa, integration of HIV and SU services is limited. We sought to unders
Repeated false-negative HIV rapid test results in a patient presenting to care with advanced HIV disease: a case report (Publications)
Severe immunosuppression has been reported as one of the causes of a false-negative HIV rapid test result. Guidelines on what tests should be performed in adult patients presenting with severe immunos
Guillain-Barré syndrome associated with COVID-19 infection: a case series (Publications)
In this communication, we reported a series of six patients presented with Guillain-Barre syndrome that associated with COVID-19 infection, which was confirmed with RT-PCR. Here we discuss the laborat
7-<em>N</em>-substituted-3-oxadiazole quinolones with potent antimalarial activity target the cytochrome <em>bc</em>1 complex (Publications)
The development of new antimalarials is required because of the threat of resistance to current antimalarial therapies. To discover new antimalarial chemotypes, we screened the Janssen Jumpstarter lib
Seasonal drivers and risks of aquatic pesticide pollution in drought and post-drought conditions in three Mediterranean watersheds (Publications)
The Western Cape in South Africa has a Mediterranean climate, which has in part led to an abundance of agriculturally productive land supporting the wheat, deciduous fruit, wine, and citrus industries
Interactions between immunity and metabolism: contributions from the metabolic profiling of parasite-rodent models (Publications)
A combined interdisciplinary research strategy is even more crucial in immunology than in many other biological sciences in order to comprehend the closely linked interactions between cell proliferati
Changes in metabolic phenotypes of <em>Plasmodium falciparum</em> <em>in vitro</em> cultures during gametocyte development (Publications)
BACKGROUND: Gametocytes are the Plasmodium life stage that is solely responsible for malaria transmission. Despite their important role in perpetuating malaria, gametocyte differentiation and developm
Discovery of infection associated metabolic markers in human African trypanosomiasis (Publications)
Human African trypanosomiasis (HAT) remains a major neglected tropical disease in Sub-Saharan Africa. As clinical symptoms are usually non-specific, new diagnostic and prognostic markers are urgently
Generating super-shedders: co-infection increases bacterial load and egg production of a gastrointestinal helminth (Publications)
Co-infection by multiple parasites is common within individuals. Interactions between co-infecting parasites include resource competition, direct competition and immune-mediated interactions and each
Metabolic characterization of <em>Leishmania major</em> infection in activated and nonactivated macrophages (Publications)
Infection with Leishmania spp. can lead to a range of symptoms in the affected individual, depending on underlying immune-metabolic processes. The macrophage activation state hereby plays a key role.
