Interferons direct an effective innate response to Legionella pneumophila infection (Publications)
Legionella pneumophila remains an important opportunistic pathogen of human macrophages. Its more limited ability to replicate in murine macrophages has been attributed to redundant innate sensor syst
Alcohol consumption and other lifestyle factors: avoidable sources of excess lead exposure (Publications)
Lead concentration in whole blood of a representative sample of 471 subjects aged 20 to 74 years and living in Basle was determined in 1989/90 by flame atomic absorption spectrophotometry. The partici
Long-term outcome in elderly patients with chronic angina managed invasively versus by optimized medical therapy: four-year follow-up of the... (Publications)
BACKGROUND: There are no prospective trial data on long-term outcomes in 80-year-old patients with chronic angina with regard to antiischemic therapy. METHODS AND RESULTS: To assess long-term survival
Isolation of aerucyclamides C and D and structure revision of microcyclamide 7806A: heterocyclic ribosomal peptides from <em>Microcystis... (Publications)
Aerucyclamides C and D were isolated from the cyanobacterium Microcystis aeruginosa PCC 7806, and their structures established by NMR spectroscopy and chemical transformation and degradation. Acidic h
IGFBP2 and IGFBP3 protein expressions in human breast cancer: association with hormonal factors and obesity (Publications)
PURPOSE: The insulin-like growth factor (IGF) signaling system is involved in breast cancer initiation and progression. The prognostic relevance of tumor expression patterns of IGFI-related proteins r
Antiprotozoal activities of heterocyclic-substituted xanthones from the marine-derived fungus <em>Chaetomium</em> sp (Publications)
Investigations of the marine-derived fungus Chaetomium sp. led to the isolation of the new natural products chaetoxanthones A, B, and C (1-3). Compounds 1 and 2 are substituted with a dioxane/tetrahyd
Ferrocenyl derivatives of the anthelmintic praziquantel: design, synthesis and biological evaluation (Publications)
The design, synthesis and biological evaluation of eighteen ferrocenyl derivatives (4A-12A and 4B-12B) of the most-well known drug against schistosomiasis, namely praziquantel (PZQ), are reported. The
Cultural epidemiology of neurasthenia spectrum disorders in four general hospital outpatient clinics of urban Pune, India (Publications)
Disorders emphasizing symptoms of fatigue and/or weakness, collectively termed Neurasthenia Spectrum Disorders (NSDs), typically emphasize a biological basis in the West and social origins in East Asi
