Natural products active against African trypanosomes: a step towards new drugs (Publications)
This review covers compounds with activity on African trypanosomes (mainly Trypanosoma brucei subsp.,T congolense and T vivax) isolated from natural sources and is organized according to the structure
<em>Trypanosoma brucei </em>CTP synthetase: a target for the treatment of African sleeping sickness (Publications)
The drugs in clinical use against African sleeping sickness are toxic, costly, or inefficient. We show that Trypanosoma brucei, which causes this disease, has very low levels of CTP, which are due to
