High sensitivity detection of <em>Plasmodium</em> species reveals positive correlations between infections of different species, shifts in age... (Publications)
BACKGROUND: When diagnosed by standard light microscopy (LM), malaria prevalence can vary significantly between sites, even at local scale, and mixed species infections are consistently less common th
Spatially-explicit risk profiling of<em> Plasmodium falciparum</em> infections at a small scale: a geostatistical modelling approach (Publications)
BACKGROUND: There is a renewed political will and financial support to eradicate malaria. Spatially-explicit risk profiling will play an important role in this endeavour. Patterns of Plasmodium falcip
Ensemble modeling of the likely public health impact of a pre-erythrocytic malaria vaccine (Publications)
BACKGROUND: The RTS,S malaria vaccine may soon be licensed. Models of impact of such vaccines have mainly considered deployment via the World Health Organization's Expanded Programme on Immunization (
MER41 repeat sequences contain inducible STAT1 binding sites (Publications)
Chromatin immunoprecipitation combined with massively parallel sequencing methods (ChIP-seq) is becoming the standard approach to study interactions of transcription factors (TF) with genomic sequence
Improving community coverage of oral cholera mass vaccination campaigns: lessons learned in Zanzibar (Publications)
BACKGROUND: Recent research in two cholera-endemic communities of Zanzibar has shown that a majority (?94%) of the adult population was willing to receive free oral cholera vaccines (OCVs). Since OCV
Identification of compounds with anti-proliferative activity against <em>Trypanosoma brucei brucei</em> strain 427 by a whole cell viability based HTS... (Publications)
Human African Trypanosomiasis (HAT) is caused by two trypanosome sub-species, Trypanosoma brucei rhodesiense and Trypanosoma brucei gambiense. Drugs available for the treatment of HAT have significant
Dynamics of <em>Schistosoma haematobium</em> egg output and associated infection parameters following treatment with praziquantel in school-aged... (Publications)
ABSTRACT: BACKGROUND: Praziquantel is the drug of choice in preventive chemotherapy targeting schistosomiasis. Increasing large-scale administration of praziquantel requires monitoring of drug efficac
<em>Anopheles plumbeus</em> (Diptera: Culicidae) in Europe: a mere nuisance mosquito or potential malaria vector? (Publications)
ABSTRACT: BACKGROUND: Anopheles plumbeus has been recognized as a minor vector for human malaria in Europe since the beginning of the 20th century. In recent years this tree hole breeding mosquito spe
