AMBITION-cm: intermittent high dose AmBisome on a high dose fluconazole backbone for cryptococcal meningitis induction therapy in sub-Saharan Africa:... (Publications)
BACKGROUND: Cryptococcal meningitis (CM) is a leading cause of mortality among HIV-infected individuals in Africa. Poor outcomes from conventional antifungal therapies, unavailability of flucytosine,
Repurposing of anticancer drugs: <em>in vitro</em> and<em> in vivo</em> activities against <em>Schistosoma mansoni</em> (Publications)
BACKGROUND: Drug discovery for the neglected tropical disease schistosomiasis has a high priority. Anticancer drugs, especially protein kinase inhibitors, might serve as a starting point for drug disc
Maturation and mip-1beta production of cytomegalovirus-specific T cell responses in Tanzanian children, adolescents and adults: impact by HIV and... (Publications)
It is well accepted that aging and HIV infection are associated with quantitative and functional changes of CMV-specific T cell responses. We studied here the expression of Mip-1beta and the T cell ma
Osteopathology and selenium deficiency co-occurring in a population of endangered Patagonian huemul (<em>Hippocamelus bisulcus</em>) (Publications)
BACKGROUND: About 1,000 endangered Patagonian huemul deer (Hippocamelus bisulcus) remain in Chile and 350-500 in Argentina. Most groups (> 100) are not recovering, and prevalence of osteopathology in
Do holes in long-lasting insecticidal nets compromise their efficacy against pyrethroid resistant <em>Anopheles gambiae</em> and <em>Culex... (Publications)
BACKGROUND: Resistance of malaria vectors to pyrethroids threatens the effectiveness of long-lasting insecticidal nets (LLINs) as a tool for malaria control. Recent experimental hut and observational
Implementation of the global plan for insecticide resistance management in malaria vectors: progress, challenges and the way forward (Publications)
In recent years, there has been an increase in resistance of malaria vectors to insecticides, particularly to pyrethroids which are widely used in insecticide-treated nets. The Global Plan for Insecti
An operational comparative study of quinine and artesunate for the treatment of severe malaria in hospitals and health centres in the Democratic... (Publications)
BACKGROUND: The Democratic Republic of the Congo (DRC) has the highest number of severe malaria cases in the world. In early 2012, the National Malaria Control Programme (NMCP) changed the policy for
