The stem region of premembrane protein plays an important role in the virus surface protein rearrangement during dengue maturation (Publications)
Newly assembled dengue viruses (DENV) undergo maturation to become infectious particles. The maturation process involves major rearrangement of virus surface premembrane (prM) and envelope (E) protein
The 1992-1999 World Bank Schistosomiasis Research Initiative in China: outcome and perspectives (Publications)
Ongoing efforts over the last 50 years, aiming at the elimination of schistosomiasis in the People's Republic of China, have been spectaculary successful in reducing the prevalence and intensity of th
Fluorinated rhodacyanine (SJL-01) possessing high efficacy for visceral leishmaniasis (VL) (Publications)
Anti-Leishmania in vitro and in vivo activities of various rhodacyanine derivatives have been examined. Among them, the fluorinatied variant SJL-01 (8) showed IC(50) of 0.011 microM against Leishmania
Soil-transmitted helminth infection in South America: a systematic review and geostatistical meta-analysis (Publications)
BACKGROUND: The four common soil-transmitted helminth species-Ascaris lumbricoides, Trichuris trichiura, and the two hookworm species Ancylostoma duodenale and Necator americanus-are endemic in South
Timeliness and completeness of vaccination and risk factors for low and late vaccine uptake in young children living in rural southern Tanzania (Publications)
Background: We studied coverage and timeliness of vaccination and risk factors for low and delayed vaccine uptake in children aged ,2 years in rural Tanzania. Methods: We used data from a cluster surv
Genetic diversity in <em>Mycobacterium tuberculosis</em> (Publications)
Recent years have witnessed an increased appreciation of the extent and relevance of strain-to-strain variation in Mycobacterium tuberculosis. This paradigm shift can largely be attributed to an impro
Chronic burden of near-roadway traffic pollution in 10 European cities (APHEKOM network) (Publications)
Recent epidemiological research suggests that near road traffic-related pollution may cause chronic disease, as well as exacerbate related pathologies, implying that the entire "chronic disease progre