Modifications and hybrids of 1,2,3,4‑tetrahydropyridinium salts and their antiprotozoal potencies (Publications)
The antiprotozoal activity of 1-benzyltetrahydropyridin-4-yliden iminium salts is reported. This paper describes the preparation of a series of analogs from dihydropyridines or dihydrothiopyrans as ed
Teaching and learning for change: analysis of a post‑graduate One Health program (Publications)
As problematized through the One Health concept, global health issues are defeating conventional disciplinary approaches since they unfold across various scientific domains and across all levels of so
Time to scale up molecular surveillance for anti-malarial drug resistance in sub-Saharan Africa (Publications)
Artemisinin resistance has emerged and spread in the Greater Mekong Sub-region (GMS), followed by artemisinin-based combination therapy failure, due to both artemisinin and partner drug resistance. Mo
Estimating intervention effectiveness in trials of malaria interventions with contamination (Publications)
Background In cluster randomized trials (CRTs) or stepped wedge cluster randomized trials (SWCRTs) of malaria interventions, mosquito movement leads to contamination between trial arms unless buffer z
Extracellular matrix-induced GM-CSF and hypoxia promote immune control of<em> Mycobacterium tuberculosis </em>in human <em>in vitro</em> granulomas (Publications)
Several in vitro cellular models have been developed with the aim to reproduce and dissect human granulomatous responses, the hallmark of tuberculosis (TB) immunopathogenesis. In that context, we comp
Early life adversity, biological adaptation, and human capital: evidence from an interrupted malaria control program in Zambia (Publications)
Growing evidence from evolutionary biology demonstrates how early life shocks trigger physiological changes designed to be adaptive in challenging environments. We examine the implications of one type
Risk profiling and efficacy of albendazole against the hookworms<em> Necator americanus </em>and <em>Ancylostoma ceylanicum</em> in Cambodia to... (Publications)
Background: Hookworm disease is endemic throughout many parts of the Asia Pacific, despite targeted control programs of at-risk populations. The success of these programs has been hindered by the limi
Nonrandom selection and multiple blood feeding of human hosts by <em>Anopheles </em>vectors: implications for malaria transmission in Papua New Guinea (Publications)
Nonrandom selection and multiple blood feeding of human hosts by Anopheles mosquitoes may exacerbate malaria transmission. Both patterns of blood feeding and their relationship to malaria epidemiology
Hygroline derivatives from <em>Schizanthus tricolor </em>and their anti-trypanosomatid and antiplasmodial activities (Publications)
Chemical investigation of the alkaloid extract of the aerial parts of Schizanthus tricolor led to the targeted isolation of 26 hygroline derivatives of which 20 were fully characterized. They have not
