Molecular surveillance of the antifolateresistant mutation I164L in imported African isolates of <em>Plasmodium falciparum</em> in Europe: sentinel... (Publications)
BACKGROUND: Malaria parasites that carry the DHFR-mutation I164L are not only highly resistant to sulfadoxine-pyrimethamine but also to the new antimalarial drug chlorproguanil-dapsone. The spread of
Nuclear factor I genomic binding associates with chromatin boundaries (Publications)
BACKGROUND: The Nuclear Factor I (NFI) family of DNA binding proteins (also called CCAAT box transcription factors or CTF) is involved in both DNA replication and gene expression regulation. Using chr
Estimating <em>Plasmodium falciparum</em> transmission rates in low-endemic settings using a combination of community prevalence and health facility... (Publications)
As some malaria control programs shift focus from disease control to transmission reduction, there is a need for transmission data to monitor progress. At lower levels of transmission, it becomes incr
Sleeping sickness in travelers - do they really sleep? (Publications)
The number of imported Human African Trypanosomiasis (HAT) cases in non-endemic countries has increased over the last years. The objective of this analysis is to describe the clinical presentation of
Effect of sanitation on soil-transmitted helminth infection: systematic review and meta-analysis (Publications)
BACKGROUND: In countries of high endemicity of the soil-transmitted helminth parasites Ascaris lumbricoides, Trichuris trichiura, and hookworm, preventive chemotherapy (i.e., repeated administration o
A high-resolution geospatial surveillance-response system for malaria elimination in Solomon Islands and Vanuatu (Publications)
BACKGROUND: A high-resolution surveillance-response system has been developed within a geographic information system (GIS) to support malaria elimination in the Pacific. This paper examines the applic
