Exposure of <em>Heligmosomoides polygyrus</em> and <em>Trichuris muris</em> to albendazole, albendazole sulfoxide, mebendazole and oxantel pamoate... (Publications)
Millions of people are treated with anthelmintics to control soil-transmitted helminth infections; yet, drug distribution in the plasma and gastrointestinal tract compartments and the pathway of drug
False-negative malaria rapid diagnostic tests in Rwanda: impact of <em>Plasmodium falciparum</em> isolates lacking <em>hrp2</em> and declining malaria... (Publications)
BACKGROUND: Rapid diagnostic tests (RDTs) for histidine rich protein 2 (HRP2) are often used to determine whether persons with fever should be treated with anti-malarials. However, Plasmodium falcipar
Controlling schistosomiasis with praziquantel: how much longer without a viable alternative? (Publications)
The current approach of morbidity control of schistosomiasis, a helminth disease of poverty with considerable public health and socioeconomic impact, is based on preventive chemotherapy with praziquan
Assessing and managing wounds of Buruli ulcer patients at the primary and secondary health care levels in Ghana (Publications)
BACKGROUND: Beyond Mycobacterium ulcerans-specific therapy, sound general wound management is required for successful management of Buruli ulcer (BU) patients which places them among the large and div
Arylmethylamino steroids as antiparasitic agents (Publications)
In search of antiparasitic agents, we here identify arylmethylamino steroids as potent compounds and characterize more than 60 derivatives. The lead compound 1o is fast acting and highly active agains
Genomic analysis of ST88 community-acquired methicillin resistant <em>Staphylococcus aureus</em> in Ghana (Publications)
BACKGROUND: The emergence and evolution of community-acquired methicillin resistant Staphylococcus aureus (CA-MRSA) strains in Africa is poorly understood. However, one particular MRSA lineage called