Antigenicity and immunogenicity of a novel chimeric peptide antigen based on the <em>P. vivax</em> circumsporozoite protein (Publications)
BACKGROUND: Plasmodium vivax circumsporozoite (PvCS) protein is a major sporozoite surface antigen involved in parasite invasion of hepatocytes and is currently being considered as vaccine candidate.
Signifikant kürzere Anästhesiezeit bei lumbaler Wirbelsäulenchirurgie: prozessanalytischer Vergleich von Spinalanästhesie und Intubationsnarkose (Publications)
INTRODUCTION: Most surgery of the lumbar spine is performed with the patient under general anesthesia (GA); however, qualitative benefits of spinal anesthesia (SA) have been reported. The goal of this
Synthesis and antiprotozoal activity of dicationic m-terphenyl and 1,3-dipyridylbenzene derivatives (Publications)
4,4''-Diamidino-m-terphenyl (1) and 36 analogues were prepared and assayed in vitro against T rypanosoma brucei rhodesiense , Trypanosoma cruzi , Plasmodium falciparum , and Leishmania amazonensis . T
Efficacy and pharmacokinetics of OZ78 and MT04 against a natural infection with <em>Fasciola hepatica</em> in sheep (Publications)
Fasciolosis is a parasitosis caused by the food-borne trematode Fasciola spp. of major veterinary significance. Triclabendazole is the first line treatment in humans and animals but cases of resistanc
Missed opportunities among HIV-positive women to control viral replication during pregnancy and to have a vaginal delivery (Publications)
INTRODUCTION:: Most national guidelines for the prevention of mother-to-child transmission of HIV in Europe updated between 2001 and 2010 recommend vaginal deliveries for women with undetectable or ve
Patients routinely report more symptoms to experienced field enumerators than physicians in rural Côte d'Ivoire (Publications)
Medical history-taking is among the most powerful diagnostic tools for healthcare professionals. However, its accuracy and reliability are underexplored areas. The present post-hoc study compares medi
Prevalence of drug-resistance mutations and HIV-1 subtypes in a HIV-1 infected COHORT in rural Tanzania (Publications)
ABSTRACT The development of resistance mutations in drug-targeted HIV-1 genes compromises the success of antiretroviral therapy (ART) programmes. Genotyping of these mutations enables adjusted therape